Public datasets are often used to evaluate the efficacy and generalizability of state-of-the-art methods for many tasks in natural language processing (NLP). However, the presence of overlap between the train and test datasets can lead to inflated results, inadvertently evaluating the model’s ability to memorize and interpreting it as the ability to generalize. In addition, such data sets may not provide an effective indicator of the performance of these methods in real world scenarios. We identify leakage of training data into test data on several publicly available datasets used to evaluate NLP tasks, including named entity recognition and relation extraction, and study them to assess the impact of that leakage on the model’s ability to memorize versus generalize.

Chemical patents contain rich coreference and bridging links, which are the target of this research. Specially, we introduce a novel annotation scheme, based on which we create the ChEMU-Ref dataset from reaction description snippets in English-language chemical patents. We propose a neural approach to anaphora resolution, which we show to achieve strong results, especially when jointly trained over coreference and bridging links.

In developing systems to identify focus entities in scientific literature, we face the problem of discriminating key entities of interest from other potentially relevant entities of the same type mentioned in the articles. We introduce the task of pathogen characterisation. We aim to discriminate mentions of biological pathogens, that are actively studied in the research presented in scientific publications. These are the pathogens that are the focus of direct experimentation in the research, rather than those that are referred to for context or as playing secondary roles. In this paper, we explore the hypothesis that these focus entities can be differentiated from other, non-actively studied, pathogens mentioned in articles through analysis of the patterns of mentions across different sections of a scientific paper, that is, using the discourse structure of the paper. We provide an indicative case study with the help of a small data set of PubMed abstracts that have been annotated with actively mentioned pathogens.

Domain pretraining followed by task fine-tuning has become the standard paradigm for NLP tasks, but requires in-domain labelled data for task fine-tuning. To overcome this, we propose to utilise domain unlabelled data by assigning pseudo labels from a general model. We evaluate the approach on two clinical STS datasets, and achieve r= 0.80 on N2C2-STS. Further investigation reveals that if the data distribution of unlabelled sentence pairs is closer to the test data, we can obtain better performance. By leveraging a large general-purpose STS dataset and small-scale in-domain training data, we obtain further improvements to r= 0.90, a new SOTA.

Efficient discovery and exploration of biomedical literature has grown in importance in the context of the COVID-19 pandemic, and topic-based methods such as latent Dirichlet allocation (LDA) are a useful tool for this purpose. In this study we compare traditional topic models based on word tokens with topic models based on medical concepts, and propose several ways to improve topic coherence and specificity.

In this paper, we apply pre-trained language models to the Semantic Textual Similarity (STS) task, with a specific focus on the clinical domain. In low-resource setting of clinical STS, these large models tend to be impractical and prone to overfitting. Building on BERT, we study the impact of a number of model design choices, namely different fine-tuning and pooling strategies. We observe that the impact of domain-specific fine-tuning on clinical STS is much less than that in the general domain, likely due to the concept richness of the domain. Based on this, we propose two data augmentation techniques. Experimental results on N2C2-STS 1 demonstrate substantial improvements, validating the utility of the proposed methods.

Identifying the reasons for antibiotic administration in veterinary records is a critical component of understanding antimicrobial usage patterns. This informs antimicrobial stewardship programs designed to fight antimicrobial resistance, a major health crisis affecting both humans and animals in which veterinarians have an important role to play. We propose a document classification approach to determine the reason for administration of a given drug, with particular focus on domain adaptation from one drug to another, and instance selection to minimize annotation effort.

We present our work on aligning the Unified Medical Language System (UMLS) to Wikipedia, to facilitate manual alignment of the two resources. We propose a cross-lingual neural reranking model to match a UMLS concept with a Wikipedia page, which achieves a recall@1of 72%, a substantial improvement of 20% over word- and char-level BM25, enabling manual alignment with minimal effort. We release our resources, including ranked Wikipedia pages for 700k UMLSconcepts, and WikiUMLS, a dataset for training and evaluation of alignment models between UMLS and Wikipedia collected from Wikidata. This will provide easier access to Wikipedia for health professionals, patients, and NLP systems, including in multilingual settings.

Chemical patents are an important resource for chemical information. However, few chemical Named Entity Recognition (NER) systems have been evaluated on patent documents, due in part to their structural and linguistic complexity. In this paper, we explore the NER performance of a BiLSTM-CRF model utilising pre-trained word embeddings, character-level word representations and contextualized ELMo word representations for chemical patents. We compare word embeddings pre-trained on biomedical and chemical patent corpora. The effect of tokenizers optimized for the chemical domain on NER performance in chemical patents is also explored. The results on two patent corpora show that contextualized word representations generated from ELMo substantially improve chemical NER performance w.r.t. the current state-of-the-art. We also show that domain-specific resources such as word embeddings trained on chemical patents and chemical-specific tokenizers, have a positive impact on NER performance.

In the fourth edition of the WMT Biomedical Translation task, we considered a total of six languages, namely Chinese (zh), English (en), French (fr), German (de), Portuguese (pt), and Spanish (es). We performed an evaluation of automatic translations for a total of 10 language directions, namely, zh/en, en/zh, fr/en, en/fr, de/en, en/de, pt/en, en/pt, es/en, and en/es. We provided training data based on MEDLINE abstracts for eight of the 10 language pairs and test sets for all of them. In addition to that, we offered a new sub-task for the translation of terms in biomedical terminologies for the en/es language direction. Higher BLEU scores (close to 0.5) were obtained for the es/en, en/es and en/pt test sets, as well as for the terminology sub-task. After manual validation of the primary runs, some submissions were judged to be better than the reference translations, for instance, for de/en, en/es and es/en.

This paper focuses on a traditional relation extraction task in the context of limited annotated data and a narrow knowledge domain. We explore this task with a clinical corpus consisting of 200 breast cancer follow-up treatment letters in which 16 distinct types of relations are annotated. We experiment with an approach to extracting typed relations called window-bounded co-occurrence (WBC), which uses an adjustable context window around entity mentions of a relevant type, and compare its performance with a more typical intra-sentential co-occurrence baseline. We further introduce a new bag-of-concepts (BoC) approach to feature engineering based on the state-of-the-art word embeddings and word synonyms. We demonstrate the competitiveness of BoC by comparing with methods of higher complexity, and explore its effectiveness on this small dataset.

Extracting chemical reactions from patents is a crucial task for chemists working on chemical exploration. In this paper we introduce the novel task of detecting the textual spans that describe or refer to chemical reactions within patents. We formulate this task as a paragraph-level sequence tagging problem, where the system is required to return a sequence of paragraphs which contain a description of a reaction. To address this new task, we construct an annotated dataset from an existing proprietary database of chemical reactions manually extracted from patents. We introduce several baseline methods for the task and evaluate them over our dataset. Through error analysis, we discuss what makes the task complex and challenging, and suggest possible directions for future research.

We investigate the incorporation of character-based word representations into a standard CNN-based relation extraction model. We experiment with two common neural architectures, CNN and LSTM, to learn word vector representations from character embeddings. Through a task on the BioCreative-V CDR corpus, extracting relationships between chemicals and diseases, we show that models exploiting the character-based word representations improve on models that do not use this information, obtaining state-of-the-art result relative to previous neural approaches.

We compare the use of LSTM-based and CNN-based character-level word embeddings in BiLSTM-CRF models to approach chemical and disease named entity recognition (NER) tasks. Empirical results over the BioCreative V CDR corpus show that the use of either type of character-level word embeddings in conjunction with the BiLSTM-CRF models leads to comparable state-of-the-art performance. However, the models using CNN-based character-level word embeddings have a computational performance advantage, increasing training time over word-based models by 25% while the LSTM-based character-level word embeddings more than double the required training time.

Machine translation enables the automatic translation of textual documents between languages and can facilitate access to information only available in a given language for non-speakers of this language, e.g. research results presented in scientific publications. In this paper, we provide an overview of the Biomedical Translation shared task in the Workshop on Machine Translation (WMT) 2018, which specifically examined the performance of machine translation systems for biomedical texts. This year, we provided test sets of scientific publications from two sources (EDP and Medline) and for six language pairs (English with each of Chinese, French, German, Portuguese, Romanian and Spanish). We describe the development of the various test sets, the submissions that we received and the evaluations that we carried out. We obtained a total of 39 runs from six teams and some of this year’s BLEU scores were somewhat higher that last year’s, especially for teams that made use of biomedical resources or state-of-the-art MT algorithms (e.g. Transformer). Finally, our manual evaluation scored automatic translations higher than the reference translations for German and Spanish.

We propose a novel neural network model for joint part-of-speech (POS) tagging and dependency parsing. Our model extends the well-known BIST graph-based dependency parser (Kiperwasser and Goldberg, 2016) by incorporating a BiLSTM-based tagging component to produce automatically predicted POS tags for the parser. On the benchmark English Penn treebank, our model obtains strong UAS and LAS scores at 94.51% and 92.87%, respectively, producing 1.5+% absolute improvements to the BIST graph-based parser, and also obtaining a state-of-the-art POS tagging accuracy at 97.97%. Furthermore, experimental results on parsing 61 “big” Universal Dependencies treebanks from raw texts show that our model outperforms the baseline UDPipe (Straka and Strakova, 2017) with 0.8% higher average POS tagging score and 3.6% higher average LAS score. In addition, with our model, we also obtain state-of-the-art downstream task scores for biomedical event extraction and opinion analysis applications. Our code is available together with all pre-trained models at: https://github.com/datquocnguyen/jPTDP

We describe SemEval–2017 Task 3 on Community Question Answering. This year, we reran the four subtasks from SemEval-2016: (A) Question–Comment Similarity, (B) Question–Question Similarity, (C) Question–External Comment Similarity, and (D) Rerank the correct answers for a new question in Arabic, providing all the data from 2015 and 2016 for training, and fresh data for testing. Additionally, we added a new subtask E in order to enable experimentation with Multi-domain Question Duplicate Detection in a larger-scale scenario, using StackExchange subforums. A total of 23 teams participated in the task, and submitted a total of 85 runs (36 primary and 49 contrastive) for subtasks A–D. Unfortunately, no teams participated in subtask E. A variety of approaches and features were used by the participating systems to address the different subtasks. The best systems achieved an official score (MAP) of 88.43, 47.22, 15.46, and 61.16 in subtasks A, B, C, and D, respectively. These scores are better than the baselines, especially for subtasks A–C.

Systems that locate mentions of concepts from ontologies in free text are known as ontology concept recognition systems. This paper describes an approach to the evaluation of the workings of ontology concept recognition systems through use of a structured test suite and presents a publicly available test suite for this purpose. It is built using the principles of descriptive linguistic fieldwork and of software testing. More broadly, we also seek to investigate what general principles might inform the construction of such test suites. The test suite was found to be effective in identifying performance errors in an ontology concept recognition system. The system could not recognize 2.1% of all canonical forms and no non-canonical forms at all. Regarding the question of general principles of test suite construction, we compared this test suite to a named entity recognition test suite constructor. We found that they had twenty features in total and that seven were shared between the two models, suggesting that there is a core of feature types that may be applicable to test suite construction for any similar type of application.