Machine reading comprehension (MRC) has achieved significant progress on the open domain in recent years, mainly due to large-scale pre-trained language models. However, it performs much worse in specific domains such as the medical field due to the lack of extensive training data and professional structural knowledge neglect. As an effort, we first collect a large scale medical multi-choice question dataset (more than 21k instances) for the National Licensed Pharmacist Examination in China. It is a challenging medical examination with a passing rate of less than 14.2% in 2018. Then we propose a novel reading comprehension model KMQA, which can fully exploit the structural medical knowledge (i.e., medical knowledge graph) and the reference medical plain text (i.e., text snippets retrieved from reference books). The experimental results indicate that the KMQA outperforms existing competitive models with a large margin and passes the exam with 61.8% accuracy rate on the test set.

The prediction of the relationship between the disease with genes and its mutations is a very important knowledge extraction task that can potentially help drug discovery. In this paper, we present our approaches for trigger word detection (task 1) and the identification of its thematic role (task 2) in AGAC track of BioNLP Open Shared Task 2019. Task 1 can be regarded as the traditional name entity recognition (NER), which cultivates molecular phenomena related to gene mutation. Task 2 can be regarded as relation extraction which captures the thematic roles between entities. For two tasks, we exploit the pre-trained biomedical language representation model (i.e., BERT) in the pipe of information extraction for the collection of mutation-disease knowledge from PubMed. And also, we design a fine-tuning technique and extra features by using multi-task learning. The experiment results show that our proposed approaches achieve 0.60 (ranks 1) and 0.25 (ranks 2) on task 1 and task 2 respectively in terms of F₁ metric.

The lack of large-scale question matching corpora greatly limits the development of matching methods in question answering (QA) system, especially for non-English languages. To ameliorate this situation, in this paper, we introduce a large-scale Chinese question matching corpus (named LCQMC), which is released to the public1. LCQMC is more general than paraphrase corpus as it focuses on intent matching rather than paraphrase. How to collect a large number of question pairs in variant linguistic forms, which may present the same intent, is the key point for such corpus construction. In this paper, we first use a search engine to collect large-scale question pairs related to high-frequency words from various domains, then filter irrelevant pairs by the Wasserstein distance, and finally recruit three annotators to manually check the left pairs. After this process, a question matching corpus that contains 260,068 question pairs is constructed. In order to verify the LCQMC corpus, we split it into three parts, i.e., a training set containing 238,766 question pairs, a development set with 8,802 question pairs, and a test set with 12,500 question pairs, and test several well-known sentence matching methods on it. The experimental results not only demonstrate the good quality of LCQMC but also provide solid baseline performance for further researches on this corpus.