Few-shot classification requires classifiers to adapt to new classes with only a few training instances. State-of-the-art meta-learning approaches such as MAML learn how to initialize and fast adapt parameters from limited instances, which have shown promising results in few-shot classification. However, existing meta-learning models solely rely on implicit instance-based statistics, and thus suffer from instance unreliability and weak interpretability. To solve this problem, we propose a novel meta-information guided meta-learning (MIML) framework, where semantic concepts of classes provide strong guidance for meta-learning in both initialization and adaptation. In effect, our model can establish connections between instance-based information and semantic-based information, which enables more effective initialization and faster adaptation. Comprehensive experimental results on few-shot relation classification demonstrate the effectiveness of the proposed framework. Notably, MIML achieves comparable or superior performance to humans with only one shot on FewRel evaluation.