Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is limited by high computational costs and restricted multimodal reasoning ability. Small language models (SLMs) are efficient but lack advanced reasoning for integrating multimodal medical data. In addition, both LLMs and SLMs lack domain knowledge for trustworthy reasoning. Therefore, we propose ClinRaGen, enhancing SLMs by leveraging LLM-derived reasoning ability via rationale distillation and domain knowledge injection for trustworthy multimodal rationale generation. Key innovations include a sequential rationale distillation framework that equips SLMs with LLM-comparable multimodal reasoning abilities, and a knowledge-augmented attention mechanism that jointly unifies multimodal representation from time series and textual data in the same encoding space, enabling it to be naturally interpreted by SLMs while incorporating domain knowledge for reliable rationale generation. Experiments on real-world medical datasets show that ClinRaGen achieves state-of-the-art performance in disease diagnosis and rationale generation, demonstrating the effectiveness of combining LLM-driven reasoning with knowledge augmentation for improved interpretability.

Visual mathematical reasoning, as a fundamental visual reasoning ability, has received widespread attention from the Large Multimodal Models (LMMs) community. Existing benchmarks mainly focus more on the end-to-end performance, but neglect the underlying principles of knowledge acquisition and generalization. Instead, we introduce WE-MATH, the first benchmark specifically designed to explore the problem-solving principles. We meticulously collect 6.5K visual math problems and decompose them into 10.9K step-level questions for evaluation, spanning 5 layers of knowledge granularity and 67 hierarchical knowledge concepts. Specifically, we decompose composite problems into sub-problems according to the required knowledge concepts and introduce a novel four-dimensional metric to hierarchically assess inherent issues in LMMs’ reasoning process. With WE-MATH, we conduct a thorough evaluation of existing LMMs in visual mathematical reasoning and provide comprehensive analysis and insight for future development. We anticipate that WE-MATH will open new pathways for advancements in visual mathematical reasoning for LMMs. Data and code are available at https://github.com/We-Math/We-Math.

Oracle Bone Script (OBS) is a vital treasure of human civilization, rich in insights from ancient societies. However, the evolution of written language over millennia complicates its decipherment. In this paper, we propose V-Oracle, an innovative framework that utilizes Large Multi-modal Models (LMMs) for interpreting OBS. V-Oracle applies principles of pictographic character formation and frames the task as a visual question-answering (VQA) problem, establishing a multi-step reasoning chain. It proposes a multi-dimensional data augmentation for synthesizing high-quality OBS samples, and also implements a multi-phase oracle alignment tuning to improve LMMs’ visual reasoning capabilities. Moreover, to bridge the evaluation gap in the OBS field, we further introduce Oracle-Bench, a comprehensive benchmark that emphasizes process-oriented assessment and incorporates both standard and out-of-distribution setups for realistic evaluation. Extensive experimental results can demonstrate the effectiveness of our method in providing quantitative analyses and superior deciphering capability.

Large language models (LLMs) have shown remarkable performance in vision-language tasks, but their application in the medical field remains underexplored, particularly for integrating structured time series data with unstructured clinical notes. In clinical practice, dynamic time series data, such as lab test results, capture critical temporal patterns, while clinical notes provide rich semantic context. Merging these modalities is challenging due to the inherent differences between continuous signals and discrete text. To bridge this gap, we introduce ProMedTS, a novel self-supervised multimodal framework that employs prompt-guided learning to unify these heterogeneous data types. Our approach leverages lightweight anomaly detection to generate anomaly captions that serve as prompts, guiding the encoding of raw time series data into informative prompt embeddings. These prompt embeddings are aligned with textual representations in a shared latent space, preserving fine-grained temporal nuances alongside semantic insights. Furthermore, our framework incorporates tailored self-supervised objectives to enhance both intra- and inter-modal alignment. We evaluate ProMedTS on disease diagnosis tasks using real-world datasets, and the results demonstrate that our method consistently outperforms state-of-the-art approaches.

Driven by recent advances in neural networks, various Deep Embedding Clustering (DEC) based short text clustering models are being developed. In these works, latent representation learning and text clustering are performed simultaneously. Although these methods are becoming increasingly popular, they use pure cluster-oriented objectives, which can produce meaningless representations. To alleviate this problem, several improvements have been developed to introduce additional learning objectives in the clustering process, such as models based on contrastive learning. However, existing efforts rely heavily on learning meaningful representations at the instance level. They have limited focus on learning global representations, which are necessary to capture the overall data structure at the cluster level. In this paper, we propose a novel DEC model, which we named the deep embedded clustering model with cluster-level representation learning (DECCRL) to jointly learn cluster and instance level representations. Here, we extend the embedded topic modelling approach to introduce reconstruction constraints to help learn cluster-level representations. Experimental results on real-world short text datasets demonstrate that our model produces meaningful clusters.