Prader-Willi syndrome
Other names | Labhart-Willi syndrome, Prader's syndrome, Prader-Labhart-Willi-Fanconi syndrome
Pronunciation | /ˈ p r ɑː d ər ˈ v ɪ l i/, /ˈ p r eɪ d ər w ɪ l i/, /ˈ p r ɑː d ər ˈ w ɪ l i/
Specialty | Medical genetics, psychiatry, pediatrics
Symptoms | Babies: weak muscles, poor feeding, slow development Children: constantly hungry, intellectual impairment, behavioural problems
Complications | Obesity, type 2 diabetes
Duration | Lifelong
Causes | Genetic disorder (typically new mutation)
Differential diagnosis | Spinal muscular atrophy, congenital myotonic dystrophy, familial obesity
Treatment | Feeding tubes, strict food supervision, exercise program, counseling
Medication | Growth hormone therapy
Frequency | 1 in 10,000–30,000 people