Down syndrome
Other names | Down's syndrome, Down's, trisomy 21
Specialty | Medical genetics, pediatrics
Symptoms | Delayed physical growth, characteristic facial features, mild to moderate intellectual disability
Causes | Third copy of chromosome 21
Risk factors | Older mother, prior affected child
Diagnostic method | Prenatal screening, genetic testing
Treatment | Educational support, sheltered work environment
Prognosis | Life expectancy 50 to 60 (developed world)
Frequency | 5.4 million (0.1%)
Deaths | 26,500 (2015)