This paper describes TenTrans’ submission to WMT21 Multilingual Low-Resource Translation shared task for the Romance language pairs. This task focuses on improving translation quality from Catalan to Occitan, Romanian and Italian, with the assistance of related high-resource languages. We mainly utilize back-translation, pivot-based methods, multilingual models, pre-trained model fine-tuning, and in-domain knowledge transfer to improve the translation quality. On the test set, our best-submitted system achieves an average of 43.45 case-sensitive BLEU scores across all low-resource pairs. Our data, code, and pre-trained models used in this work are available in TenTrans evaluation examples.