Automatic diagnosis (AD), a critical application of AI in healthcare, employs machine learning techniques to assist doctors in gathering patient symptom information for precise disease diagnosis. The Transformer-based method utilizes an input symptom sequence, predicts itself through auto-regression, and employs the hidden state of the final symptom to determine the disease. Despite its simplicity and superior performance demonstrated, a decline in disease diagnosis accuracy is observed caused by 1) a mismatch between symptoms observed during training and generation, and 2) the effect of different symptom orders on disease prediction. To address the above obstacles, we introduce the CoAD, a novel disease and symptom collaborative generation framework, which incorporates several key innovations to improve AD: 1) aligning sentence-level disease labels with multiple possible symptom inquiry steps to bridge the gap between training and generation; 2) expanding symptom labels for each sub-sequence of symptoms to enhance annotation and eliminate the effect of symptom order; 3) developing a repeated symptom input schema to effectively and efficiently learn the expanded disease and symptom labels. We evaluate the CoAD framework using four datasets, including three public and one private, and demonstrate that it achieves an average 2.3% improvement over previous state-of-the-art results in automatic disease diagnosis. For reproducibility, we release the code and data at https://github.com/KwanWaiChung/coad.

Generating persona consistent dialogue response is important for developing an intelligent conversational agent. Recent works typically fine-tune large-scale pre-trained models on this task by concatenating persona texts and dialogue history as a single input sequence to generate the target response. While simple and effective, our analysis shows that this popular practice is seriously affected by order sensitivity where different input orders of persona sentences significantly impact the quality and consistency of generated response, resulting in severe performance fluctuations (i.e., 29.4% on GPT2 and 83.2% on BART). To mitigate the order sensitivity problem, we propose a model-agnostic framework, ORder Insensitive Generation (ORIG), which enables dialogue models to learn robust representation under different persona orders and improve the consistency of response generation. Experiments on the Persona-Chat dataset justify the effectiveness and superiority of our method with two dominant pre-trained models (GPT2 and BART).