Enhancing Adverse Drug Event Detection with Multimodal Dataset: Corpus Creation and Model Development

Pranab Sahoo, Ayush Singh, Sriparna Saha, Aman Chadha, Samrat Mondal


Abstract
The mining of adverse drug events (ADEs) is pivotal in pharmacovigilance, enhancing patient safety by identifying potential risks associated with medications, facilitating early detection of adverse events, and guiding regulatory decision-making. Traditional ADE detection methods are reliable but slow, not easily adaptable to large-scale operations, and offer limited information. With the exponential increase in data sources like social media content, biomedical literature, and Electronic Medical Records (EMR), extracting relevant ADE-related information from these unstructured texts is imperative. Previous ADE mining studies have focused on text-based methodologies, overlooking visual cues, limiting contextual comprehension, and hindering accurate interpretation. To address this gap, we present a MultiModal Adverse Drug Event (MMADE) detection dataset, merging ADE-related textual information with visual aids. Additionally, we introduce a framework that leverages the capabilities of LLMs and VLMs for ADE detection by generating detailed descriptions of medical images depicting ADEs, aiding healthcare professionals in visually identifying adverse events. Using our MMADE dataset, we showcase the significance of integrating visual cues from images to enhance overall performance. This approach holds promise for patient safety, ADE awareness, and healthcare accessibility, paving the way for further exploration in personalized healthcare.
Anthology ID:
2024.findings-acl.667
Volume:
Findings of the Association for Computational Linguistics ACL 2024
Month:
August
Year:
2024
Address:
Bangkok, Thailand and virtual meeting
Editors:
Lun-Wei Ku, Andre Martins, Vivek Srikumar
Venue:
Findings
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
11214–11226
Language:
URL:
https://aclanthology.org/2024.findings-acl.667
DOI:
Bibkey:
Cite (ACL):
Pranab Sahoo, Ayush Singh, Sriparna Saha, Aman Chadha, and Samrat Mondal. 2024. Enhancing Adverse Drug Event Detection with Multimodal Dataset: Corpus Creation and Model Development. In Findings of the Association for Computational Linguistics ACL 2024, pages 11214–11226, Bangkok, Thailand and virtual meeting. Association for Computational Linguistics.
Cite (Informal):
Enhancing Adverse Drug Event Detection with Multimodal Dataset: Corpus Creation and Model Development (Sahoo et al., Findings 2024)
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https://preview.aclanthology.org/nschneid-patch-4/2024.findings-acl.667.pdf