We present Reddit Health Online Talk (RedHOT), a corpus of 22,000 richly annotated social media posts from Reddit spanning 24 health conditions. Annotations include demarcations of spans corresponding to medical claims, personal experiences, and questions. We collect additional granular annotations on identified claims. Specifically, we mark snippets that describe patient Populations, Interventions, and Outcomes (PIO elements) within these. Using this corpus, we introduce the task of retrieving trustworthy evidence relevant to a given claim made on social media. We propose a new method to automatically derive (noisy) supervision for this task which we use to train a dense retrieval model; this outperforms baseline models. Manual evaluation of retrieval results performed by medical doctors indicate that while our system performance is promising, there is considerable room for improvement. We release all annotations collected (and scripts to assemble the dataset), and all code necessary to reproduce the results in this paper at: https://sominw.com/redhot.

Identification of medical claims from user-generated text data is an onerous but essential step for various tasks including content moderation, and hypothesis generation. SemEval-2023 Task 8 is an effort towards building those capabilities and motivating further research in this direction. This paper summarizes the details and results of shared task 8 at SemEval-2023 which involved identifying causal medical claims and extracting related Populations, Interventions, and Outcomes (“PIO”) frames from social media (Reddit) text. This shared task comprised two subtasks: (1) Causal claim identification; and (2) PIO frame extraction. In total, seven teams participated in the task. Of the seven, six provided system descriptions which we summarize here. For the first subtask, the best approach yielded a macro-averaged F-1 score of 78.40, and for the second subtask, the best approach achieved token-level F-1 scores of 40.55 for Populations, 49.71 for Interventions, and 30.08 for Outcome frames.

Relation extraction (RE) is the core NLP task of inferring semantic relationships between entities from text. Standard supervised RE techniques entail training modules to tag tokens comprising entity spans and then predict the relationship between them. Recent work has instead treated the problem as a sequence-to-sequence task, linearizing relations between entities as target strings to be generated conditioned on the input. Here we push the limits of this approach, using larger language models (GPT-3 and Flan-T5 large) than considered in prior work and evaluating their performance on standard RE tasks under varying levels of supervision. We address issues inherent to evaluating generative approaches to RE by doing human evaluations, in lieu of relying on exact matching. Under this refined evaluation, we find that: (1) Few-shot prompting with GPT-3 achieves near SOTA performance, i.e., roughly equivalent to existing fully supervised models; (2) Flan-T5 is not as capable in the few-shot setting, but supervising and fine-tuning it with Chain-of-Thought (CoT) style explanations (generated via GPT-3) yields SOTA results. We release this model as a new baseline for RE tasks.

Recent work has shown that fine-tuning large networks is surprisingly sensitive to changes in random seed(s). We explore the implications of this phenomenon for model fairness across demographic groups in clinical prediction tasks over electronic health records (EHR) in MIMIC-III —— the standard dataset in clinical NLP research. Apparent subgroup performance varies substantially for seeds that yield similar overall performance, although there is no evidence of a trade-off between overall and subgroup performance. However, we also find that the small sample sizes inherent to looking at intersections of minority groups and somewhat rare conditions limit our ability to accurately estimate disparities. Further, we find that jointly optimizing for high overall performance and low disparities does not yield statistically significant improvements. Our results suggest that fairness work using MIMIC-III should carefully account for variations in apparent differences that may arise from stochasticity and small sample sizes.

The ability to track mental health conditions via social media opened the doors for large-scale, automated, mental health surveillance. However, inferring accurate population-level trends requires representative samples of the underlying population, which can be challenging given the biases inherent in social media data. While previous work has adjusted samples based on demographic estimates, the populations were selected based on specific outcomes, e.g. specific mental health conditions. We depart from these methods, by conducting analyses over demographically representative digital cohorts of social media users. To validated this approach, we constructed a cohort of US based Twitter users to measure the prevalence of depression and PTSD, and investigate how these illnesses manifest across demographic subpopulations. The analysis demonstrates that cohort-based studies can help control for sampling biases, contextualize outcomes, and provide deeper insights into the data.