@inproceedings{chen-etal-2025-towards-medical,
    title = "Towards Medical Complex Reasoning with {LLM}s through Medical Verifiable Problems",
    author = "Chen, Junying  and
      Cai, Zhenyang  and
      Ji, Ke  and
      Wang, Xidong  and
      Liu, Wanlong  and
      Wang, Rongsheng  and
      Wang, Benyou",
    editor = "Che, Wanxiang  and
      Nabende, Joyce  and
      Shutova, Ekaterina  and
      Pilehvar, Mohammad Taher",
    booktitle = "Findings of the Association for Computational Linguistics: ACL 2025",
    month = jul,
    year = "2025",
    address = "Vienna, Austria",
    publisher = "Association for Computational Linguistics",
    url = "https://preview.aclanthology.org/mtsummit-25-ingestion/2025.findings-acl.751/",
    doi = "10.18653/v1/2025.findings-acl.751",
    pages = "14552--14573",
    ISBN = "979-8-89176-256-5",
    abstract = "The breakthrough of OpenAI o1 highlights the potential of enhancing reasoning to improve LLM. Yet, most research in reasoning has focused on mathematical tasks, leaving domains like medicine underexplored. The medical domain, though distinct from mathematics, also demands robust reasoning to provide reliable answers, given the high standards of healthcare. However, verifying medical reasoning is challenging, unlike those in mathematics. To address this, we propose **Medical Verifiable Problems** with a medical verifier to check the correctness of model outputs. This verifiable nature enables advancements in medical reasoning through **a two-stage approach**: (1) using the verifier to guide the search for a complex reasoning trajectory for fine-tuning LLMs, (2) applying reinforcement learning (RL) with verifier-based rewards to enhance complex reasoning further. Finally, we introduce HuatuoGPT-o1, a medical LLM capable of complex reasoning, which outperforms general and medical-specific baselines using only 40K verifiable problems. Experiments show complex reasoning improves medical problem-solving and benefits more from RL. We hope our approach inspires advancements in reasoning across medical and other specialized domains. Code, datasets, and models are publicly available at https://github.com/FreedomIntelligence/HuatuoGPT-o1."
}