Recent advancements in Vision Language Models (VLMs) have demonstrated remarkable promise in generating visually grounded responses. However, their application in the medical domain is hindered by unique challenges. For instance, most VLMs rely on a single method of visual grounding, whereas complex medical tasks demand more versatile approaches. Additionally, while most VLMs process only 2D images, a large portion of medical images are 3D. The lack of medical data further compounds these obstacles. To address these challenges, we present VividMed, a vision language model with versatile visual grounding for medicine. Our model supports generating both semantic segmentation masks and instance-level bounding boxes, and accommodates various imaging modalities, including both 2D and 3D data. We design a three-stage training procedure and an automatic data synthesis pipeline based on open datasets and models. Besides visual grounding tasks, VividMed also excels in other common downstream tasks, including Visual Question Answering (VQA) and report generation. Ablation studies empirically show that the integration of visual grounding ability leads to improved performance on these tasks. Our code is publicly available at https://github.com/function2-llx/MMMM.

Personalized response generation is essential for more human-like conversations. However, how to model user personalization information with no explicit user persona descriptions or demographics still remains under-investigated. To tackle the data sparsity problem and the huge number of users, we utilize tensor factorization to model users’ personalization information with their posting histories. Specifically, we introduce the personalized response embedding for all question-user pairs and form them into a three-mode tensor, decomposed by Tucker decomposition. The personalized response embedding is fed to either the decoder of an LSTM-based Seq2Seq model or a transformer language model to help generate more personalized responses. To evaluate how personalized the generated responses are, we further propose a novel ranking-based metric called Per-Hits@k which measures how likely are the generated responses come from the corresponding users. Results on a large-scale conversation dataset show that our proposed tensor factorization based models generate more personalized and higher quality responses compared to baselines.

Further pre-training language models on in-domain data (domain-adaptive pre-training, DAPT) or task-relevant data (task-adaptive pre-training, TAPT) before fine-tuning has been shown to improve downstream tasks’ performances. However, in task-oriented dialog modeling, we observe that further pre-training MLM does not always boost the performance on a downstream task. We find that DAPT is beneficial in the low-resource setting, but as the fine-tuning data size grows, DAPT becomes less beneficial or even useless, and scaling the size of DAPT data does not help. Through Representational Similarity Analysis, we conclude that more data for fine-tuning yields greater change of the model’s representations and thus reduces the influence of initialization.