Automatic Evaluation of Healthcare LLMs Beyond Question-Answering

Anna Arias-Duart, Pablo Agustin Martin-Torres, Daniel Hinjos, Pablo Bernabeu-Perez, Lucia Urcelay Ganzabal, Marta Gonzalez Mallo, Ashwin Kumar Gururajan, Enrique Lopez-Cuena, Sergio Alvarez-Napagao, Dario Garcia-Gasulla


Abstract
Current Large Language Models (LLMs) benchmarks are often based on open-ended or close-ended QA evaluations, avoiding the requirement of human labor. Close-ended measurements evaluate the factuality of responses but lack expressiveness. Open-ended capture the model’s capacity to produce discourse responses but are harder to assess for correctness. These two approaches are commonly used, either independently or together, though their relationship remains poorly understood. This work is focused on the healthcare domain, where both factuality and discourse matter greatly. It introduces a comprehensive, multi-axis suite for healthcare LLM evaluation, exploring correlations between open and close benchmarks and metrics. Findings include blind spots and overlaps in current methodologies. As an updated sanity check, we release a new medical benchmark–CareQA–, with both open and closed variants. Finally, we propose a novel metric for open-ended evaluations –Relaxed Perplexity– to mitigate the identified limitations.
Anthology ID:
2025.naacl-short.10
Volume:
Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (Volume 2: Short Papers)
Month:
April
Year:
2025
Address:
Albuquerque, New Mexico
Editors:
Luis Chiruzzo, Alan Ritter, Lu Wang
Venue:
NAACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
108–130
Language:
URL:
https://preview.aclanthology.org/moar-dois/2025.naacl-short.10/
DOI:
10.18653/v1/2025.naacl-short.10
Bibkey:
Cite (ACL):
Anna Arias-Duart, Pablo Agustin Martin-Torres, Daniel Hinjos, Pablo Bernabeu-Perez, Lucia Urcelay Ganzabal, Marta Gonzalez Mallo, Ashwin Kumar Gururajan, Enrique Lopez-Cuena, Sergio Alvarez-Napagao, and Dario Garcia-Gasulla. 2025. Automatic Evaluation of Healthcare LLMs Beyond Question-Answering. In Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (Volume 2: Short Papers), pages 108–130, Albuquerque, New Mexico. Association for Computational Linguistics.
Cite (Informal):
Automatic Evaluation of Healthcare LLMs Beyond Question-Answering (Arias-Duart et al., NAACL 2025)
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PDF:
https://preview.aclanthology.org/moar-dois/2025.naacl-short.10.pdf