ClinicalTrialsHub: Bridging Registries and Literature for Comprehensive Clinical Trial Access

Jiwoo Park, Ruoqi Liu, Avani Jagdale, Andrew Srisuwananukorn, Jing Zhao, Lang Li, Ping Zhang, Sachin Kumar


Abstract
We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles. Our system effectively increases access to structured clinical trial data by 83.8% compared to relying on ClinicalTrials.gov alone, with potential to make access easier for patients, clinicians, researchers, and policymakers, advancing evidence-based medicine. ClinicalTrialsHub uses large language models such as GPT-5.1 and Gemini-3-Pro to enhance accessibility. The platform automatically parses full-text research articles to extract structured trial information, translates user queries into structured database searches, and provides an attributed question-answering system that generates evidence-grounded answers linked to specific source sentences. We demonstrate its utility through a user study involving clinicians, clinical researchers, and PhD students of pharmaceutical sciences and nursing, and a systematic automatic evaluation of its information extraction and question answering capabilities.
Anthology ID:
2026.eacl-demo.26
Volume:
Proceedings of the 19th Conference of the European Chapter of the Association for Computational Linguistics (Volume 3: System Demonstrations)
Month:
March
Year:
2026
Address:
Rabat, Marocco
Editors:
Danilo Croce, Jochen Leidner, Nafise Sadat Moosavi
Venue:
EACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
359–396
Language:
URL:
https://preview.aclanthology.org/missing-isa-paper/2026.eacl-demo.26/
DOI:
10.18653/v1/2026.eacl-demo.26
Bibkey:
Cite (ACL):
Jiwoo Park, Ruoqi Liu, Avani Jagdale, Andrew Srisuwananukorn, Jing Zhao, Lang Li, Ping Zhang, and Sachin Kumar. 2026. ClinicalTrialsHub: Bridging Registries and Literature for Comprehensive Clinical Trial Access. In Proceedings of the 19th Conference of the European Chapter of the Association for Computational Linguistics (Volume 3: System Demonstrations), pages 359–396, Rabat, Marocco. Association for Computational Linguistics.
Cite (Informal):
ClinicalTrialsHub: Bridging Registries and Literature for Comprehensive Clinical Trial Access (Park et al., EACL 2026)
Copy Citation:
PDF:
https://preview.aclanthology.org/missing-isa-paper/2026.eacl-demo.26.pdf