Recent studies have explored Continual Instruction Tuning (CIT) in Multimodal Large Language Models (MLLMs), with a primary focus on Task-incremental CIT, where MLLMs are required to continuously acquire new tasks. However, the more practical and challenging Domain-incremental CIT, focused on the continual adaptation of MLLMs to new domains, remains underexplored. In this paper, we propose a new Sparse Mixture of Expert (SMoE) based method for domain-incremental CIT in MLLMs. During training, we learn a domain-specific SMoE module for each new domain in every FFN sub-layer of MLLMs, preventing catastrophic forgetting caused by inter-domain conflicts. Moreover, we equip the SMoE module with a domain-specific autoregressive loss (DSAL), which is used to identify the most suitable SMoE module for processing each test instruction during inference. To further enhance the SMoE module’s ability to learn domain knowledge, we design an adaptive threshold-based router (AT-Router) that allocates computing resources (experts) to instruction tokens based on their importance. Finally, we establish a new benchmark to evaluate the efficacy of our method and advance future research. Extensive experiments show that our method consistently outperforms all competitive baselines.

Misinformation spans various domains, but detection methods trained on specific domains often perform poorly when applied to others. With the rapid development of Large Language Models (LLMs), researchers have begun to utilize LLMs for cross-domain misinformation detection. However, existing LLM-based methods often fail to adequately analyze news in the target domain, limiting their detection capabilities. More importantly, these methods typically rely on manually designed decision rules, which are limited by domain knowledge and expert experience, thus limiting the generalizability of decision rules to different domains. To address these issues, we propose a Multi-Agent Framework for cross-domain misinformation detection with Automated Decision Rule Optimization (MARO). Under this framework, we first employs multiple expert agents to analyze target-domain news. Subsequently, we introduce a question-reflection mechanism that guides expert agents to facilitate higher-quality analysis. Furthermore, we propose a decision rule optimization approach based on carefully designed cross-domain validation tasks to iteratively enhance decision rule effectiveness across domains. Experimental results and analysis on commonly used datasets demonstrate that MARO achieves significant improvements over existing methods.