Dialogue policy trains an agent to select dialogue actions frequently implemented via deep reinforcement learning (DRL). The model-based reinforcement methods built a world model to generate simulated data to alleviate the sample inefficiency. However, traditional world model methods merely consider one-step dialogues, leading to an inaccurate environmental simulation. Furthermore, different users may have different intention preferences, while most existing studies lack consideration of the intention-preferences causal relationship. This paper proposes a novel framework for dialogue policy learning named MCA, implemented through model-based reinforcement learning with automatically constructed causal chains. The MCA model utilizes an autoregressive Transformer to model dialogue trajectories, enabling a more accurate simulation of the environment. Additionally, it constructs a causal chains module that outputs latent preference distributions for intention-action pairs, thereby elucidating the relationship between user intentions and agent actions. The experimental results show that MCA can achieve state-of-the-art performances on three dialogue datasets over the compared dialogue agents, highlighting its effectiveness and robustness.

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling, RNA structure prediction, protein function inference, and single-cell transcriptomics. Meanwhile, we also discuss several key challenges, including data scarcity, computational complexity, and cross-omics integration, and explore future directions such as multimodal learning, hybrid AI models, and clinical applications. By offering a comprehensive perspective, this paper underscores the transformative potential of LLMs in driving innovations in bioinformatics and precision medicine.

Training a task-oriented dialogue policy using deep reinforcement learning is promising but requires extensive environment exploration. The amount of wasted invalid exploration makes policy learning inefficient. In this paper, we define and argue that dead-end states are important reasons for invalid exploration. When a conversation enters a dead-end state, regardless of the actions taken afterward, it will continue in a dead-end trajectory until the agent reaches a termination state or maximum turn. We propose a Dead-end Detection and Resurrection (DDR) method that detects dead-end states in an efficient manner and provides a rescue action to guide and correct the exploration direction. To prevent dialogue policies from repeating errors, DDR also performs dialogue data augmentation by adding relevant experiences that include dead-end states and penalties into the experience pool. We first validate the dead-end detection reliability and then demonstrate the effectiveness and generality of the method across various domains through experiments on four public dialogue datasets.

“Domain-specific text classification often needs more external knowledge, and fraud cases havefewer descriptions. Existing methods usually utilize single-stage deep models to extract semanticfeatures, which is less reusable. To tackle this issue, we propose a two-stage training frameworkbased on within-task pretraining and multi-dimensional semantic enhancement for CCL23-EvalTask 6 (Telecom Network Fraud Case Classification, FCC). Our training framework is dividedinto two stages. First, we pre-train using the training corpus to obtain specific BERT. The seman-tic mining ability of the model is enhanced from the feature space perspective by introducing ad-versarial training and multiple random sampling. The pseudo-labeled data is generated throughthe test data above a certain threshold. Second, pseudo-labeled samples are added to the trainingset for semantic enhancement based on the sample space dimension. We utilize the same back-bone for prediction to obtain the results. Experimental results show that our proposed methodoutperforms the single-stage benchmarks and achieves competitive performance with 0.859259F1. It also performs better in the few-shot patent classification task with 65.160% F1, whichindicates robustness.”

Large language models (LLMs) have been widely applied in various fields due to their excellent capability for memorizing knowledge and chain of thought (CoT). When these language models are applied in the field of psychological counseling, they often rush to provide universal advice. However, when users seek psychological support, they need to gain empathy, trust, understanding and comfort, rather than just reasonable advice. To this end, we constructed a multi-turn empathetic conversation dataset of more than 2 million samples, in which the input is the multi-turn conversation context, and the target is empathetic responses that cover expressions such as questioning, comfort, recognition, listening, trust, emotional support, etc. Experiments have shown that the empathy ability of LLMs can be significantly enhanced when finetuning by using multi-turn dialogue history and responses that are closer to the expression of a psychological consultant.

Deep reinforcement learning has shown great potential in training dialogue policies. However, its favorable performance comes at the cost of many rounds of interaction. Most of the existing dialogue policy methods rely on a single learning system, while the human brain has two specialized learning and memory systems, supporting to find good solutions without requiring copious examples. Inspired by the human brain, this paper proposes a novel complementary policy learning (CPL) framework, which exploits the complementary advantages of the episodic memory (EM) policy and the deep Q-network (DQN) policy to achieve fast and effective dialogue policy learning. In order to coordinate between the two policies, we proposed a confidence controller to control the complementary time according to their relative efficacy at different stages. Furthermore, memory connectivity and time pruning are proposed to guarantee the flexible and adaptive generalization of the EM policy in dialog tasks. Experimental results on three dialogue datasets show that our method significantly outperforms existing methods relying on a single learning system.