Relation classification is to determine the semantic relationship between two entities in a given sentence. However, many relation classifiers are vulnerable to adversarial attacks, which is using adversarial examples to lead victim models to output wrong results. In this paper, we propose a simple but effective method for misleading relation classifiers. We first analyze the most important parts of speech (POSs) from the syntax and morphology perspectives, then we substitute words labeled with these POS tags in original samples with synonyms or hyponyms. Experimental results show that our method can generate adversarial texts of high quality, and most of the relationships between entities can be correctly identified in the process of human evaluation. Furthermore, the adversarial examples generated by our method possess promising transferability, and they are also helpful for improving the robustness of victim models.