Recent advances in large language models (LLMs) have significantly improved automated code generation, enabling tools such as GitHub Copilot and CodeWhisperer to assist developers in a wide range of programming tasks. However, the translation of complex mobile UI designs into high-fidelity front-end code remains a challenging and underexplored area, especially as modern app interfaces become increasingly intricate. In this work, we propose UIOrchestra, a collaborative multi-agent system designed for the AppUI2Code task, which aims to reconstruct static single-page applications from design mockups. UIOrchestra integrates three specialized agents, layout description, code generation, and difference analysis agent that work collaboratively to address the limitations of single-model approaches. To facilitate robust evaluation, we introduce APPUI, the first benchmark dataset for AppUI2Code, constructed through a human-in-the-loop process to ensure data quality and coverage. Experimental results demonstrate that UIOrchestra outperforms existing methods in reconstructing complex app pages and highlight the necessity of multi-agent collaboration for this task. We hope our work will inspire further research on leveraging LLMs for front-end automation. The code and data will be released upon paper acceptance.