In this paper, we describe TTIC’s submission to WMT 2023 Sign Language Translation task on the Swiss-German Sign Language (DSGS) to German track. Our approach explores the advantages of using large-scale self-supervised pre-training in the task of sign language translation, over more traditional approaches that rely heavily on supervision, along with costly labels such as gloss annotations. The proposed model consists of a VideoSwin transformer for image encoding, and a T5 model adapted to receive VideoSwin features as input instead of text. In WMT-SLT 22’s development set, this system achieves 2.03 BLEU score, a 59% increase over the previous best reported performance. In the official test set, our primary submission achieves 1.1 BLEU score and 17.0 chrF score.