Research in computational linguistics, computer graphics and autonomous agents has led to the development of increasingly sophisticated communicative agents over the past few years, bringing new perspective to machine translation research. The engineering of language- based smooth, expressive, natural-looking human gestures can give us useful insights into the design principles that have evolved in natural communication between people. In this paper we prototype a machine translation system from English to American Sign Language (ASL), taking into account not only linguistic but also visual and spatial information associated with ASL signs.