We present a biomedical knowledge enhanced pre-trained language model for medicinal product vertical search. Following ELECTRA’s replaced token detection (RTD) pre-training, we leverage biomedical entity masking (EM) strategy to learn better contextual word representations. Furthermore, we propose a novel pre-training task, product attribute prediction (PAP), to inject product knowledge into the pre-trained language model efficiently by leveraging medicinal product databases directly. By sharing the parameters of PAP’s transformer encoder with that of RTD’s main transformer, these two pre-training tasks are jointly learned. Experiments demonstrate the effectiveness of PAP task for pre-trained language model on medicinal product vertical search scenario, which includes query-title relevance, query intent classification, and named entity recognition in query.