Multi-hop relation detection in Knowledge Base Question Answering (KBQA) aims at retrieving the relation path starting from the topic entity to the answer node based on a given question, where the relation path may comprise multiple relations. Most of the existing methods treat it as a single-label learning problem while ignoring the fact that for some complex questions, there exist multiple correct relation paths in knowledge bases. Therefore, in this paper, multi-hop relation detection is considered as a multi-label learning problem. However, performing multi-label multi-hop relation detection is challenging since the numbers of both the labels and the hops are unknown. To tackle this challenge, multi-label multi-hop relation detection is formulated as a sequence generation task. A relation-aware sequence relation generation model is proposed to solve the problem in an end-to-end manner. Experimental results show the effectiveness of the proposed method for relation detection and KBQA.