Hateful memes continuously evolve as new ones emerge by blending progressive cultural ideas, rendering existing methods that rely on extensive training obsolete or ineffective. In this work, we propose Evolver, which incorporates Large Multimodal Models (LMMs) via Chain-of-Evolution (CoE) Prompting, by integrating the evolution attribute and in-context information of memes. Specifically, Evolver simulates the evolving and expressing process of memes and reasons through LMMs in a step-by-step manner using an evolutionary pair mining module, an evolutionary information extractor, and a contextual relevance amplifier. Extensive experiments on public FHM, MAMI, and HarM datasets show that CoE prompting can be incorporated into existing LMMs to improve their performance. More encouragingly, it can serve as an interpretive tool to promote the understanding of the evolution of memes.

Hallucination has emerged as a critical challenge for large language models (LLMs) and large vision-language models (LVLMs), particularly in high-stakes medical applications. Despite its significance, dedicated research on medical hallucination remains unexplored. In this survey, we first provide a unified perspective on medical hallucination for both LLMs and LVLMs, and delve into its causes. Subsequently, we review recent advancements in detecting, evaluating, and mitigating medical hallucinations, offering a comprehensive overview of evaluation benchmarks, metrics, and strategies developed to tackle this issue. Moreover, we delineate the current challenges and delve into new frontiers, thereby shedding light on future research. We hope this work coupled with open-source resources can provide the community with quick access and spur breakthrough research in medical hallucination.

Electrocardiogram (ECG) is the primary non-invasive diagnostic tool for monitoring cardiac conditions and is crucial in assisting clinicians. Recent studies have concentrated on classifying cardiac conditions using ECG data but have overlooked ECG report generation, which is time-consuming and requires clinical expertise. To automate ECG report generation and ensure its versatility, we propose the Multimodal ECG Instruction Tuning (MEIT) framework, the first attempt to tackle ECG report generation with LLMs and multimodal instructions. To facilitate future research, we establish a benchmark to evaluate MEIT with various LLMs backbones across two large-scale ECG datasets. Our approach uniquely aligns the representations of the ECG signal and the report, and we conduct extensive experiments to benchmark MEIT with nine open-source LLMs using more than 800,000 ECG reports. MEIT’s results underscore the superior performance of instruction-tuned LLMs, showcasing their proficiency in quality report generation, zero-shot capabilities, resilience to signal perturbation, and alignment with human expert evaluation. These findings emphasize the efficacy of our MEIT framework and its potential for real-world clinical application.

Medical Vision-Language Pre-training (MedVLP) has made significant progress in enabling zero-shot tasks for medical image understanding. However, training MedVLP models typically requires large-scale datasets with paired, high-quality image-text data, which are scarce in the medical domain. Recent advancements in Large Language Models (LLMs) and diffusion models have made it possible to generate large-scale synthetic image-text pairs. This raises the question: Can MedVLP succeed using purely synthetic data? To address this, we use off-the-shelf generative models to create synthetic radiology reports and paired Chest X-ray (CXR) images, and propose an automated pipeline to build a diverse, high-quality synthetic dataset, enabling a rigorous study that isolates model and training settings, focusing entirely from the data perspective.Our results show that MedVLP models trained exclusively on synthetic data outperform those trained on real data by 3.8% in averaged AUC on zero-shot classification. Moreover, using a combination of synthetic and real data leads to a further improvement of 9.07%. Additionally, MedVLP models trained on synthetic or mixed data consistently outperform those trained on real data in zero-shot grounding, as well as in fine-tuned classification and segmentation tasks.Our analysis suggests MedVLP trained on well-designed synthetic data can outperform models trained on real datasets, which may be limited by low-quality samples and long-tailed distributions[^1].[^1]: All data and code will be released upon acceptance.

Automatic radiology report generation holds significant potential to streamline the labor-intensive process of report writing by radiologists, particularly for 3D radiographs such as CT scans. While CT scans are critical for clinical diagnostics, they remain less explored compared to 2D radiographs. To date, there has been no comprehensive benchmark for 3D radiograph report generation (3DRRG), nor sufficient investigation into the optimal training strategies for Vision Language Models (VLMs) in this context, particularly with respect to vision encoder choices, visual token compression, and model scaling.In this work, we make two three contributions. We curate CT-3DRRG, the largest publicly available 3D CT-report dataset, establishing a robust and diverse benchmark for evaluating VLM performance on 3DRRG. Furthermore, we propose a comprehensive training recipe for building high-performing VLMs for 3DRRG, exploring key factors such as vision encoder pretraining strategies, visual token compression, and the impact of data & model scale. Guided by these findings, we introduce Argus, a state-of-the-art family of VLMs that achieve superior performance across different model sizes and input 3D medical image resolutions, efficiently processing high-resolution 3D images up to 512 × 512 × 256.

Long-context Multimodal Large Language Models (MLLMs) that incorporate long text-image and text-video modalities, demand substantial computational resources as their multimodal Key-Value (KV) cache grows with increasing input lengths, challenging memory and time efficiency. For multimodal scenarios, the cross-modal interactions inevitablely increase complexity, and prior methods for KV cache compression, in both text-only and multimodal LLMs, have neglected attention density variations across layers, often adopting uniform or progressive reduction strategis for layer-wise cache allocation. This results in precision loss and suboptimal performance. We propose MEDA, a novel approach specifically designed for the complexities of multimodal settings, dynamically allocating KV cache sizes based on attention entropy to better adapt to multimodal interactions.Through a dynamic multimodal KV cache allocation strategy, MEDA compresses the KV cache, adaptively retains sufficient multimodal information at each layer. Meanwhile, to mitigate the degradation of contextual information due to cache compression, we also integrate KV pairs merging techniques to maintain coherence. MEDA achieves up to 72% KV cache memory reduction and 2.82 faster decoding speeds in some cases, while maintaining or enhancing performance on various multimodal tasks in a long context, including multi-image and long video scenarios.

Despite significant advancements, the practical deployment of Large Language Models (LLMs) is often hampered by their immense sizes, highlighting the need for effective compression techniques. Singular Value Decomposition (SVD) emerges as a promising method for compressing LLMs. However, existing SVD-based compression approaches suffer from substantial truncation losses, leading to severe performance degradation in compressed models. In this work, we introduce , a novel SVD-based LLM compression method that optimizes singular value truncation in SVD compression with two key strategies. First, employs dynamic compression ratio allocation to effectively balance the extremely large truncation loss across different layers. Second, it implements loss-optimized weight truncation to ensure that the truncated singular values result in a lower and more stable truncation loss in practice. We evaluate on ten datasets and five models on various scales and demonstrated that outperforms current state-of-the-art methods. The source code is available at https://github.com/AIoT-MLSys-Lab/SVD-LLM.

Long-context Multimodal Large Language Models (MLLMs) demand substantial computational resources for inference as the growth of their multimodal Key-Value (KV) cache, in response to increasing input lengths, challenges memory and time efficiency. Unlike single-modality LLMs that manage only textual contexts, the KV cache of long-context MLLMs includes representations from multiple images with temporal and spatial relationships and related textual contexts. The predominance of image tokens means traditional optimizations for LLMs’ KV caches are unsuitable for multimodal long-context settings, and no prior works have addressed this challenge.In this work, we introduce **LOOK-M**, a pioneering, fine-tuning-free approach that efficiently reduces the multimodal KV cache size while maintaining performance comparable to a full cache. We observe that during prompt prefill, the model prioritizes more textual attention over image features, and based on the multimodal interaction observation, a new proposed text-prior method is explored to compress the KV cache. Furthermore, to mitigate the degradation of image contextual information, we propose several compensatory strategies using KV pairs merging. **LOOK-M** demonstrates that with a significant reduction in KV Cache memory usage, such as reducing it by **80%** in some cases, it not only achieves approximately **1.3x** faster decoding but also maintains or even **enhances** performance across a variety of long context multimodal tasks.

General pre-trained language models (PLMs), such as BERT, have achieved remarkable performance on various NLP tasks. Recently, domain-specific PLMs have been proposed to boost the task performance of specific domains (e.g., biomedical and computer science) by continuing to pre-train general PLMs with domain-specific corpora. However, this domain-adaptive pre-training (DAPT (CITATION)) tends to forget the previous general knowledge acquired by general PLMs, which leads to a catastrophic forgetting phenomenon and sub-optimal performance. To alleviate this problem, we propose a new framework of Memory-Augmented Pre-trained Language Model (MAP), which augments the domain-specific PLM by a memory built from the frozen general PLM without losing the general knowledge. Specifically, we propose a new memory-augmented layer, and based on it, different augmentation strategies are explored to build memory and fusion memory into domain-specific PLM. We demonstrate the effectiveness of MAP on different domains (biomedical and computer science publications, news, and reviews) and different kinds (text classification, QA, NER) of tasks, and the extensive results show that the proposed MAP can achieve SOTA results on these tasks.