Active Learning (AL) allows models to learn interactively from user feedback. However, only annotating existing samples may hardly benefit the model’s generalization. Moreover, AL commonly faces a cold start problem due to insufficient annotated data for effective sample selection. To address this, we introduce a counterfactual data augmentation approach inspired by Variation Theory, a theory of human concept learning that emphasizes the essential features of a concept by focusing on what stays the same and what changes. We use a neuro-symbolic pipeline to pinpoint key conceptual dimensions and use a large language model (LLM) to generate targeted variations along those dimensions. Through a text classification experiment, we show that our approach achieves significantly higher performance when there are fewer annotated data, showing its capability to address the cold start problem in AL. We also find that as the annotated training data gets larger, the impact of the generated data starts to diminish. This work demonstrates the value of incorporating human learning theories into the design and optimization of AL.