We introduce MedGraphRAG, a novel graph-based Retrieval-Augmented Generation (RAG) framework designed to enhance LLMs in generating evidence-based medical responses, improving safety and reliability with private medical data. We introduce Triple Graph Construction and U-Retrieval to enhance GraphRAG, enabling holistic insights and evidence-based response generation for medical applications. Specifically, we connect user documents to credible medical sources and integrate Top-down Precise Retrieval with Bottom-up Response Refinement for balanced context awareness and precise indexing. Validated on 9 medical Q&A benchmarks, 2 health fact-checking datasets, and a long-form generation test set, MedGraphRAG outperforms state-of-the-art models while ensuring credible sourcing. Our code is publicly available.

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address complex problems requiring deep research. A key innovation in our framework is the Mind-Map agent, which constructs a structured knowledge graph to store reasoning context and track logical relationships, ensuring coherence in long reasoning chains with extensive tool usage. Additionally, we conduct a comprehensive exploration of the Web-Search agent, leading to a highly effective search mechanism that surpasses all prior approaches. When deployed on DeepSeek-R1, our method achieves a new state-of-the-art (SOTA) among public models and delivers performance comparable to OpenAI Deep Research, the leading proprietary model in this domain. Extensive ablation studies validate the optimal selection of agentic tools and confirm the effectiveness of our Mind-Map and Web-Search agents in enhancing LLM reasoning. Our code and data are publicly available.