While recent advances in fake news video detection have shown promising potential, existing approaches typically (1) focus on a specific domain (e.g., politics) and (2) assume the availability of multiple modalities, including video, audio, description texts, and related images. However, these methods struggle to generalize to real-world scenarios, where questionable information spans diverse domains and is often modality-incomplete due to factors such as upload degradation or missing metadata. To address these challenges, we introduce two real-world multi-domain news video benchmarks that reflect modality incompleteness and propose IMOL, an incomplete-modality-tolerant learning framework for multi-domain fake news video detection. Inspired by cognitive theories suggesting that humans infer missing modalities through cross-modal guidance and retrieve relevant knowledge from memory for reference, IMOL employs a hierarchical transferable information integration strategy. This consists of two key phases: (1) leveraging cross-modal consistency to reconstruct missing modalities and (2) refining sample-level transferable knowledge through cross-sample associative reasoning. Extensive experiments demonstrate that IMOL significantly enhances the performance and robustness of multi-domain fake news video detection while effectively generalizing to unseen domains under incomplete modality conditions.

Multimodal large language models (MLLMs) have demonstrated impressive capabilities in visual reasoning and text generation. While previous studies have explored the application of MLLM for detecting out-of-context (OOC) misinformation, our empirical analysis reveals two persisting challenges of this paradigm. Evaluating the representative GPT-4o model on direct reasoning and evidence augmented reasoning, results indicate that MLLM struggle to capture the deeper relationships—specifically, cases in which the image and text are not directly connected but are associated through underlying semantic links. Moreover, noise in the evidence further impairs detection accuracy.To address these challenges, we propose CMIE, a novel OOC misinformation detection framework that incorporates a Coexistence Relationship Generation (CRG) strategy and an Association Scoring (AS) mechanism. CMIE identifies the underlying coexistence relationships between images and text, and selectively utilizes relevant evidence to enhance misinformation detection. Experimental results demonstrate that our approach outperforms existing methods.