Humor, requiring creativity and contextual understanding, is a hallmark of human intelligence, showcasing adaptability across linguistic scenarios. While recent advances in large language models (LLMs) demonstrate strong reasoning on various benchmarks, it remains unclear whether they truly adapt to new tasks like humans (i.e., generalize) or merely replicate memorized content. To explore this, we introduce Phunny, a new humor-based question-answering benchmark designed to assess LLMs’ reasoning through carefully crafted puns. Our dataset is manually curated to ensure novelty and minimize data contamination, providing a robust evaluation of LLMs’ linguistic comprehension. Experiments on pun comprehension, resolution, and generation reveal that most LLMs struggle with generalization, even on simple tasks, consistently underperforming the human baseline. Additionally, our detailed error analysis provides valuable insights to guide future research.

Biomedical Named Entity Recognition (BioNER) faces significant challenges in real-world applications due to limited annotated data and the constant emergence of new entity types, making zero-shot learning capabilities crucial. While Large Language Models (LLMs) possess extensive domain knowledge necessary for specialized fields like biomedicine, their computational costs often make them impractical. To address these challenges, we introduce OpenBioNER, a lightweight BERT-based cross-encoder architecture that can identify any biomedical entity using only its description, eliminating the need for retraining on new, unseen entity types. Through comprehensive evaluation on established biomedical benchmarks, we demonstrate that OpenBioNER surpasses state-of-the-art baselines, including specialized 7B NER LLMs and GPT-4o, achieving up to 10% higher F1 scores while using 110M parameters only. Moreover, OpenBioNER outperforms existing small-scale models that match textual spans with entity types rather than descriptions, both in terms of accuracy and computational efficiency.

What happens when a named entity recognition (NER) system encounters entities it has never seen before? In practical applications, models must generalize to unseen entity types where labeled training data is either unavailable or severely limited—a challenge that demands zero-shot learning capabilities. While large language models (LLMs) offer extensive parametric knowledge, they fall short in cost-effectiveness compared to specialized small encoders. Existing zero-shot methods predominantly adopt a relaxed definition of the term with potential leakage issues and rely on entity type names for generalization, overlooking the value of richer descriptions for disambiguation. In this work, we introduce ZeroNER, a description-driven framework that enhances hard zero-shot NER in low-resource settings. By leveraging general-domain annotations and entity type descriptions with LLM supervision, ZeroNER enables a BERT-based student model to successfully identify unseen entity types. Evaluated on three real-world benchmarks, ZeroNER consistently outperforms LLMs by up to 16% in F1 score, and surpasses lightweight baselines that use type names alone. Our analysis further reveals that LLMs derive significant benefits from incorporating type descriptions in the prompts.

Medical open-domain question answering demands substantial access to specialized knowledge. Recent efforts have sought to decouple knowledge from model parameters, counteracting architectural scaling and allowing for training on common low-resource hardware. The retrieve-then-read paradigm has become ubiquitous, with model predictions grounded on relevant knowledge pieces from external repositories such as PubMed, textbooks, and UMLS. An alternative path, still under-explored but made possible by the advent of domain-specific large language models, entails constructing artificial contexts through prompting. As a result, “to generate or to retrieve” is the modern equivalent of Hamlet’s dilemma. This paper presents MedGENIE, the first generate-then-read framework for multiple-choice question answering in medicine. We conduct extensive experiments on MedQA-USMLE, MedMCQA, and MMLU, incorporating a practical perspective by assuming a maximum of 24GB VRAM. MedGENIE sets a new state-of-the-art in the open-book setting of each testbed, allowing a small-scale reader to outcompete zero-shot closed-book 175B baselines while using up to 706x fewer parameters. Our findings reveal that generated passages are more effective than retrieved ones in attaining higher accuracy.