Extracting scientific evidence from biomedical studies for clinical research questions (e.g., Does stem cell transplantation improve quality of life in patients with medically refractory Crohn’s disease compared to placebo?) is a crucial step in synthesising biomedical evidence. In this paper, we focus on the task of document-level scientific evidence extraction for clinical questions with conflicting evidence. To support this task, we create a dataset called CochraneForest leveraging forest plots from Cochrane systematic reviews. It comprises 202 annotated forest plots, associated clinical research questions, full texts of studies, and study-specific conclusions. Building on CochraneForest, we propose URCA (Uniform Retrieval Clustered Augmentation), a retrieval-augmented generation framework designed to tackle the unique challenges of evidence extraction. Our experiments show that URCA outperforms the best existing methods by up to 10.3% in F1 score on this task. However, the results also underscore the complexity of CochraneForest, establishing it as a challenging testbed for advancing automated evidence synthesis systems.

Due to the fast pace at which research reports in behaviour change are published, researchers, consultants and policymakers would benefit from more automatic ways to process these reports. Automatic extraction of the reports’ intervention content, population, settings and their results etc. are essential in synthesising and summarising the literature. However, to the best of our knowledge, no unique resource exists at the moment to facilitate this synthesis. In this paper, we describe the construction of a corpus of published behaviour change intervention evaluation reports aimed at smoking cessation. We also describe and release the annotation of 57 entities, that can be used as an off-the-shelf data resource for tasks such as entity recognition, etc. Both the corpus and the annotation dataset are being made available to the community.