MAGI: Multi-Agent Guided Interview for Psychiatric Assessment

Guanqun Bi, Zhuang Chen, Zhoufu Liu, Hongkai Wang, Xiyao Xiao, Yuqiang Xie, Wen Zhang, Yongkang Huang, Yuxuan Chen, Libiao Peng, Minlie Huang


Abstract
Automating structured clinical interviews could revolutionize mental healthcare accessibility, yet existing large language models (LLMs) approaches fail to align with psychiatric diagnostic protocols. We present MAGI, the first framework that transforms the gold-standard Mini International Neuropsychiatric Interview (MINI) into automatic computational workflows through coordinated multi-agent collaboration. MAGI dynamically navigates clinical logic via four specialized agents: 1) an interview tree guided navigation agent adhering to the MINI’s branching structure, 2) an adaptive question agent blending diagnostic probing, explaining, and empathy, 3) a judgment agent validating whether the response from participants meet the node, and 4) a diagnosis Agent generating Psychometric Chain-of- Thought (PsyCoT) traces that explicitly map symptoms to clinical criteria. Experimental results on 1,002 real-world participants covering depression, generalized anxiety, social anxiety and suicide shows that MAGI advances LLM- assisted mental health assessment by combining clinical rigor, conversational adaptability, and explainable reasoning.
Anthology ID:
2025.findings-acl.1278
Volume:
Findings of the Association for Computational Linguistics: ACL 2025
Month:
July
Year:
2025
Address:
Vienna, Austria
Editors:
Wanxiang Che, Joyce Nabende, Ekaterina Shutova, Mohammad Taher Pilehvar
Venue:
Findings
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Publisher:
Association for Computational Linguistics
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Pages:
24898–24921
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https://preview.aclanthology.org/landing_page/2025.findings-acl.1278/
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Cite (ACL):
Guanqun Bi, Zhuang Chen, Zhoufu Liu, Hongkai Wang, Xiyao Xiao, Yuqiang Xie, Wen Zhang, Yongkang Huang, Yuxuan Chen, Libiao Peng, and Minlie Huang. 2025. MAGI: Multi-Agent Guided Interview for Psychiatric Assessment. In Findings of the Association for Computational Linguistics: ACL 2025, pages 24898–24921, Vienna, Austria. Association for Computational Linguistics.
Cite (Informal):
MAGI: Multi-Agent Guided Interview for Psychiatric Assessment (Bi et al., Findings 2025)
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https://preview.aclanthology.org/landing_page/2025.findings-acl.1278.pdf