IITK at SemEval-2024 Task 2: Exploring the Capabilities of LLMs for Safe Biomedical Natural Language Inference for Clinical Trials

Shreyasi Mandal, Ashutosh Modi


Abstract
Large Language models (LLMs) have demonstrated state-of-the-art performance in various natural language processing (NLP) tasks across multiple domains, yet they are prone to shortcut learning and factual inconsistencies. This research investigates LLMs’ robustness, consistency, and faithful reasoning when performing Natural Language Inference (NLI) on breast cancer Clinical Trial Reports (CTRs) in the context of SemEval 2024 Task 2: Safe Biomedical Natural Language Inference for Clinical Trials. We examine the reasoning capabilities of LLMs and their adeptness at logical problem-solving. A comparative analysis is conducted on pre-trained language models (PLMs), GPT-3.5, and Gemini Pro under zero-shot settings using Retrieval-Augmented Generation (RAG) framework, integrating various reasoning chains. The evaluation yields an F1 score of 0.69, consistency of 0.71, and a faithfulness score of 0.90 on the test dataset.
Anthology ID:
2024.semeval-1.201
Volume:
Proceedings of the 18th International Workshop on Semantic Evaluation (SemEval-2024)
Month:
June
Year:
2024
Address:
Mexico City, Mexico
Editors:
Atul Kr. Ojha, A. Seza Doğruöz, Harish Tayyar Madabushi, Giovanni Da San Martino, Sara Rosenthal, Aiala Rosá
Venue:
SemEval
SIG:
SIGLEX
Publisher:
Association for Computational Linguistics
Note:
Pages:
1397–1404
Language:
URL:
https://aclanthology.org/2024.semeval-1.201
DOI:
Bibkey:
Cite (ACL):
Shreyasi Mandal and Ashutosh Modi. 2024. IITK at SemEval-2024 Task 2: Exploring the Capabilities of LLMs for Safe Biomedical Natural Language Inference for Clinical Trials. In Proceedings of the 18th International Workshop on Semantic Evaluation (SemEval-2024), pages 1397–1404, Mexico City, Mexico. Association for Computational Linguistics.
Cite (Informal):
IITK at SemEval-2024 Task 2: Exploring the Capabilities of LLMs for Safe Biomedical Natural Language Inference for Clinical Trials (Mandal & Modi, SemEval 2024)
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PDF:
https://preview.aclanthology.org/jeptaln-2024-ingestion/2024.semeval-1.201.pdf
Supplementary material:
 2024.semeval-1.201.SupplementaryMaterial.txt