Overview of the 2024 Shared Task on Chemotherapy Treatment Timeline Extraction

Jiarui Yao, Harry Hochheiser, WonJin Yoon, Eli Goldner, Guergana Savova


Abstract
The 2024 Shared Task on Chemotherapy Treatment Timeline Extraction aims to advance the state of the art of clinical event timeline extraction from the Electronic Health Records (EHRs). Specifically, this edition focuses on chemotherapy event timelines from EHRs of patients with breast, ovarian and skin cancers. These patient-level timelines present a novel challenge which involves tasks such as the extraction of relevant events, time expressions and temporal relations from each document and then summarizing over the documents. De-identified EHRs for 57,530 patients with breast and ovarian cancer spanning 2004-2020, and approximately 15,946 patients with melanoma spanning 2010-2020 were made available to participants after executing a Data Use Agreement. A subset of patients is annotated for gold entities, time expressions, temporal relations and patient-level timelines. The rest is considered unlabeled data. In Subtask1, gold chemotherapy event mentions and time expressions are provided (along with the EHR notes). Participants are asked to build the patient-level timelines using gold annotations as input. Thus, the subtask seeks to explore the topics of temporal relations extraction and timeline creation if event and time expression input is perfect. In Subtask2, which is the realistic real-world setting, only EHR notes are provided. Thus, the subtask aims at developing an end-to-end system for chemotherapy treatment timeline extraction from patient’s EHR notes. There were 18 submissions for Subtask 1 and 9 submissions for Subtask 2. The organizers provided a baseline system. The teams employed a variety of methods including Logistic Regression, TF-IDF, n-grams, transformer models, zero-shot prompting with Large Language Models (LLMs), and instruction tuning. The gap in performance between prompting LLMs and finetuning smaller-sized LMs indicates that for a challenging task such as patient-level chemotherapy timeline extraction, more sophisticated LLMs or prompting techniques are necessary in order to achieve optimal results as finetuing smaller-sized LMs outperforms by a wide margin.
Anthology ID:
2024.clinicalnlp-1.53
Volume:
Proceedings of the 6th Clinical Natural Language Processing Workshop
Month:
June
Year:
2024
Address:
Mexico City, Mexico
Editors:
Tristan Naumann, Asma Ben Abacha, Steven Bethard, Kirk Roberts, Danielle Bitterman
Venues:
ClinicalNLP | WS
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
557–569
Language:
URL:
https://aclanthology.org/2024.clinicalnlp-1.53
DOI:
Bibkey:
Cite (ACL):
Jiarui Yao, Harry Hochheiser, WonJin Yoon, Eli Goldner, and Guergana Savova. 2024. Overview of the 2024 Shared Task on Chemotherapy Treatment Timeline Extraction. In Proceedings of the 6th Clinical Natural Language Processing Workshop, pages 557–569, Mexico City, Mexico. Association for Computational Linguistics.
Cite (Informal):
Overview of the 2024 Shared Task on Chemotherapy Treatment Timeline Extraction (Yao et al., ClinicalNLP-WS 2024)
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PDF:
https://preview.aclanthology.org/jeptaln-2024-ingestion/2024.clinicalnlp-1.53.pdf