This paper presents the first neural machine translator system for the Ayuuk language. In our experiments we translate from Ayuuk to Spanish, and fromSpanish to Ayuuk. Ayuuk is a language spoken in the Oaxaca state of Mexico by the Ayuukjä’äy people (in Spanish commonly known as Mixes. We use different sources to create a low-resource parallel corpus, more than 6,000 phrases. For some of these resources we rely on automatic alignment. The proposed system is based on the Transformer neural architecture and it uses sub-word level tokenization as the input. We show the current performance given the resources we have collected for the San Juan Güichicovi variant, they are promising, up to 5 BLEU. We based our development on the Masakhane project for African languages.