As Large Language Models (LLMs) advance, aligning them with human values is critical for their responsible development. Value principles serve as the foundation for clarifying alignment goals.Multiple sets of value principles have been proposed, such as HHH (helpful, honest, harmless) and instructions for data synthesis in reinforcement learning from AI feedback (RLAIF). However, most of them are heuristically crafted, without consideration of three primary challenges in practical LLM alignment: 1) Comprehensiveness to deal with diverse and even unforeseen scenarios in which LLMs could be applied; 2) Precision to provide LLMs with clear and actionable guidance in specific scenarios; and 3) Compatability to avoid internal contracts between principles.In this paper, we formalize quantitative metrics to evaluate value principles along the three desirable properties. Building on these metrics, we propose the Hierarchical Value Principle framework (HiVaP), which constructs a hierarchical principle set and retrieves principles tailored to each scenario in a cascading way, addressing above challenges.Experimental results validate that the three metrics capture the effectiveness of value principles for LLM alignment, and our HiVaP framework that enhances these metrics leads to superior alignment. Warning: This paper contains several toxic and offensive statements.

Automatic recognition of biomedical entities in text is the crucial initial step in biomedical text mining. In this pa-per, we investigate employing modern neural network models for recognizing biomedical entities. To compensate for the small amount of training data in biomedical domain, we propose to integrate dictionaries into the neural model. Our experiments on BB3 data sets demonstrate that state-of-the-art neural network model is promising in recognizing biomedical entities even with very little training data. When integrated with dictionaries, its performance could be greatly improved, achieving the competitive performance compared with the best dictionary-based system on the entities with specific terminology, and much higher performance on the entities with more general terminology.