Audiobook interpretations are attracting increasing attention, as they provide accessible and in-depth analyses of books that offer readers practical insights and intellectual inspiration. However, their manual creation process remains time-consuming and resource-intensive. To address this challenge, we propose AI4Reading, a multi-agent collaboration system leveraging large language models (LLMs) and speech synthesis technology to generate podcast-like audiobook interpretations. The system is designed to meet three key objectives: accurate content preservation, enhanced comprehensibility, and a logical narrative structure. To achieve these goals, We develop a framework composed of 11 specialized agents—including topic analysts, case analysts, editors, a narrator, and proofreaders—that work in concert to explore themes, extract real-world cases, refine content organization, and synthesize natural spoken language. By comparing expert interpretations with our system’s output, the results show that although AI4Reading still has a gap in speech generation quality, the generated interpretative scripts are simpler and more accurate. The code of AI4Reading is publicly accessible , with a demonstration video available .