We introduce MedGraphRAG, a novel graph-based Retrieval-Augmented Generation (RAG) framework designed to enhance LLMs in generating evidence-based medical responses, improving safety and reliability with private medical data. We introduce Triple Graph Construction and U-Retrieval to enhance GraphRAG, enabling holistic insights and evidence-based response generation for medical applications. Specifically, we connect user documents to credible medical sources and integrate Top-down Precise Retrieval with Bottom-up Response Refinement for balanced context awareness and precise indexing. Validated on 9 medical Q&A benchmarks, 2 health fact-checking datasets, and a long-form generation test set, MedGraphRAG outperforms state-of-the-art models while ensuring credible sourcing. Our code is publicly available.

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address complex problems requiring deep research. A key innovation in our framework is the Mind-Map agent, which constructs a structured knowledge graph to store reasoning context and track logical relationships, ensuring coherence in long reasoning chains with extensive tool usage. Additionally, we conduct a comprehensive exploration of the Web-Search agent, leading to a highly effective search mechanism that surpasses all prior approaches. When deployed on DeepSeek-R1, our method achieves a new state-of-the-art (SOTA) among public models and delivers performance comparable to OpenAI Deep Research, the leading proprietary model in this domain. Extensive ablation studies validate the optimal selection of agentic tools and confirm the effectiveness of our Mind-Map and Web-Search agents in enhancing LLM reasoning. Our code and data are publicly available.

User profile embedded in the prompt template of personalized recommendation agents play a crucial role in shaping their decision-making process. High-quality user profiles are essential for aligning agent behavior with real user interests. Typically, these profiles are constructed by leveraging LLMs for user profile modeling (LLM-UM). However, this process faces several challenges: (1) LLMs struggle with long user behaviors due to context length limitations and performance degradation. (2) Existing methods often extract only partial segments from full historical behavior sequence, inevitably discarding diverse user interests embedded in the omitted content, leading to incomplete modeling and suboptimal profiling. (3) User profiling is often tightly coupled with the inference context, requiring online processing, which introduces significant latency overhead. In this paper, we propose PersonaX, an agent-agnostic LLM-UM framework to address these challenges. It augments downstream recommendation agents to achieve better recommendation performance and inference efficiency. PersonaX (a) segments complete historical behaviors into clustered groups, (b) selects multiple sub-behavior sequences (SBS) with a balance of prototypicality and diversity to form a high-quality core set, (c) performs offline multi-persona profiling to capture diverse user interests and generate fine-grained, cached textual personas, and (d) decouples user profiling from online inference, enabling profile retrieval instead of real-time generation. Extensive experiments demonstrate its effectiveness: using only 30–50% of behavioral data (sequence length 480), PersonaX enhances AgentCF by 3–11% and Agent4Rec by 10–50%. As a scalable and model-agnostic LLM-UM solution, PersonaX sets a new benchmark in scalable user modeling. The code is available at URL .

Traditional recommender systems usually take the user-platform paradigm, where users are directly exposed under the control of the platform’s recommendation algorithms. However, the defect of recommendation algorithms may put users in very vulnerable positions under this paradigm. First, many sophisticated models are often designed with commercial objectives in mind, focusing on the platform’s benefits, which may hinder their ability to protect and capture users’ true interests. Second, these models are typically optimized using data from all users, which may overlook individual user’s preferences. Due to these shortcomings, users may experience several disadvantages under the traditional user-platform direct exposure paradigm, such as lack of control over the recommender system, potential manipulation by the platform, echo chamber effects, or lack of personalization for less active users due to the dominance of active users during collaborative learning. Therefore, there is an urgent need to develop a new paradigm to protect user interests and alleviate these issues. Recently, some researchers have introduced LLM agents to simulate user behaviors, these approaches primarily aim to optimize platform-side performance, leaving core issues in recommender systems unresolved. To address these limitations, we propose a new user-agent-platform paradigm, where agent serves as the protective shield between user and recommender system that enables indirect exposure. To this end, we first construct four recommendation datasets, denoted as InstructRec, along with user instructions for each record. To understand user’s intention, we design an Instruction-aware Agent capable of using tools to acquire knowledge from external environments. Moreover, we introduce an Individual Instruction-aware Agent, which incorporates a dynamic memory mechanism to optimize from individual feedback. Results on four datasets demonstrate that consistently achieves an average improvement of 16.6% over SOTA baselines across ranking metrics. Moreover, iAgent mitigates echo chamber effects and effectively alleviates the model bias in disadvantaged users (less-active), serving as a shield between user and recommender systems.