Taming the Real-world Complexities in CPT E/M Coding with Large Language Models
Islam Nassar, Yang Lin, Yuan Jin, Rongxin Zhu, Chang Wei Tan, Zenan Zhai, Nitika Mathur, Thanh Tien Vu, Xu Zhong, Long Duong, Yuan-Fang Li
Abstract
Evaluation and Management (E/M) coding, under the Current Procedural Terminology (CPT) taxonomy, documents medical services provided to patients by physicians. Used primarily for billing purposes, it is in physicians’ best interest to provide accurate CPT E/M codes. Automating this coding task will help alleviate physicians’ documentation burden, improve billing efficiency, and ultimately enable better patient care. However, a number of real-world complexities have made E/M encoding automation a challenging task. In this paper, we elaborate some of the key complexities and present ProFees, our LLM-based framework that tackles them, followed by a systematic evaluation. On an expert-curated real-world dataset, ProFees achieves an increase in coding accuracy of more than 36% over a commercial CPT E/M coding system and almost 5% over our strongest single-prompt baseline, demonstrating its effectiveness in addressing the real-world complexities.- Anthology ID:
- 2025.emnlp-industry.84
- Volume:
- Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing: Industry Track
- Month:
- November
- Year:
- 2025
- Address:
- Suzhou (China)
- Editors:
- Saloni Potdar, Lina Rojas-Barahona, Sebastien Montella
- Venue:
- EMNLP
- SIG:
- Publisher:
- Association for Computational Linguistics
- Note:
- Pages:
- 1212–1226
- Language:
- URL:
- https://preview.aclanthology.org/ingest-emnlp/2025.emnlp-industry.84/
- DOI:
- Cite (ACL):
- Islam Nassar, Yang Lin, Yuan Jin, Rongxin Zhu, Chang Wei Tan, Zenan Zhai, Nitika Mathur, Thanh Tien Vu, Xu Zhong, Long Duong, and Yuan-Fang Li. 2025. Taming the Real-world Complexities in CPT E/M Coding with Large Language Models. In Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing: Industry Track, pages 1212–1226, Suzhou (China). Association for Computational Linguistics.
- Cite (Informal):
- Taming the Real-world Complexities in CPT E/M Coding with Large Language Models (Nassar et al., EMNLP 2025)
- PDF:
- https://preview.aclanthology.org/ingest-emnlp/2025.emnlp-industry.84.pdf