Anja Thieme


2026

Sentiment analysis in low-resource, culturally nuanced contexts challenges conventional NLP approaches that assume fixed labels and universal affective expressions. We present a diagnostic framework that treats sentiment as a context-dependent, culturally embedded construct, and evaluate how large language models (LLMs) reason about sentiment in informal, code-mixed WhatsApp messages from Nairobi youth health groups. Using human-annotated data, sentiment-flipped counterfactuals, and rubric-based explanation evaluation, we probe LLM interpretability, robustness, and alignment with human reasoning. Framing our evaluation through a social science measurement lens, we operationalize LLM outputs as an instrument for measuring the abstract concept of sentiment. Our findings reveal significant variation in model reasoning quality, with top-tier LLMs demonstrating greater interpretive stability, while smaller open-weight models in our study show reduced stability under ambiguity or sentiment shifts. This work highlights the need for culturally sensitive, reasoning-aware AI evaluation in complex, real-world communication.

2024

This paper discusses the participation of the MSR MAIRA team in the Large-Scale Radiology Report Generation Shared Task Challenge, as part of the BioNLP workshop at ACL 2024. We present a radiology-specific multimodal model designed to generate radiological reports from chest X-Rays (CXRs). Our proposed model combines a CXR-specific image encoder RAD-DINO with a Large Language Model (LLM) based on Vicuna-7B, via a multi-layer perceptron (MLP) adapter. Both the adapter and the LLM have been fine-tuned in a single-stage training setup to generate radiology reports. Experimental results indicate that a joint training setup with findings and impression sections improves findings prediction. Additionally, incorporating lateral images alongside frontal images when available further enhances all metrics. More information and resources about MAIRA can be found on the project website: http://aka.ms/maira.

2023

The recent success of general-domain large language models (LLMs) has significantly changed the natural language processing paradigm towards a unified foundation model across domains and applications. In this paper, we focus on assessing the performance of GPT-4, the most capable LLM so far, on the text-based applications for radiology reports, comparing against state-of-the-art (SOTA) radiology-specific models. Exploring various prompting strategies, we evaluated GPT-4 on a diverse range of common radiology tasks and we found GPT-4 either outperforms or is on par with current SOTA radiology models. With zero-shot prompting, GPT-4 already obtains substantial gains ( 10% absolute improvement) over radiology models in temporal sentence similarity classification (accuracy) and natural language inference (F1). For tasks that require learning dataset-specific style or schema (e.g. findings summarisation), GPT-4 improves with example-based prompting and matches supervised SOTA. Our extensive error analysis with a board-certified radiologist shows GPT-4 has a sufficient level of radiology knowledge with only occasional errors in complex context that require nuanced domain knowledge. For findings summarisation, GPT-4 outputs are found to be overall comparable with existing manually-written impressions.