Graph-Enhanced LLM Analysis of Multimodal Health Communities: A Computational Framework for Patient Discourse Understanding on TikTok

Tawakalit Agboola, Oluwaseun Ajao


Abstract
Social media platforms have become critical sources of patient-generated health data, yet existing computational approaches fail to capture the interconnected nature of online health discourse. We present a novel framework that integrates graph-based community detection with large language model analysis to understand patient narratives in multimodal social media content. Applied to 10,253 TikTok posts about JAK inhibitors (2020-2024), our approach constructs heterogeneous graphs representing user-content-medical entity relationships and applies community detection algorithms enhanced with context-aware LLM interpretation. Our comprehensive analysis of 10,253 posts (January 2020–September 2024) reveals five distinct patient communities characterized by different discourse patterns: treatment success narratives (873 nodes), medication guidance (642 nodes), side effect discussions (589 nodes), comparative treatment analysis (412 nodes), and dosage optimization (347 nodes). The Louvain algorithm significantly outperformed Girvan-Newman in modularity (0.9931 vs. 0.9928), conductance (0.0002 vs. 0.0006), and computational efficiency (0.14s vs. 54.24s). Temporal analysis demonstrates increasing community cohesion and evolving discourse patterns from cautious inquiry (2020-2021) to experience sharing and specialized sub-communities (2023-2024). This work contributes: (1) a scalable computational framework for multimodal health content analysis, (2) methodological innovations in graph-LLM integration, and (3) insights into platform-specific health communication patterns. The framework has applications in pharmacovigilance, computational social science, and AI-assisted health monitoring systems.
Anthology ID:
2026.healing-1.9
Volume:
Proceedings of the 1st Workshop on Linguistic Analysis for Health (HeaLing 2026)
Month:
March
Year:
2026
Address:
Rabat, Morocco
Editors:
Vera Danilova, Murathan Kurfalı, Ylva Söderfeldt, Julia Reed, Andrew Burchell
Venues:
HeaLing | WS
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Publisher:
Association for Computational Linguistics
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Pages:
105–114
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URL:
https://preview.aclanthology.org/ingest-eacl/2026.healing-1.9/
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Cite (ACL):
Tawakalit Agboola and Oluwaseun Ajao. 2026. Graph-Enhanced LLM Analysis of Multimodal Health Communities: A Computational Framework for Patient Discourse Understanding on TikTok. In Proceedings of the 1st Workshop on Linguistic Analysis for Health (HeaLing 2026), pages 105–114, Rabat, Morocco. Association for Computational Linguistics.
Cite (Informal):
Graph-Enhanced LLM Analysis of Multimodal Health Communities: A Computational Framework for Patient Discourse Understanding on TikTok (Agboola & Ajao, HeaLing 2026)
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https://preview.aclanthology.org/ingest-eacl/2026.healing-1.9.pdf