MedQA-CS: Objective Structured Clinical Examination (OSCE)-Style Benchmark for Evaluating LLM Clinical Skills

Zonghai Yao, Zihao Zhang, Chaolong Tang, Xingyu Bian, Youxia Zhao, Zhichao Yang, Junda Wang, Huixue Zhou, Won Seok Jang, Feiyun Ouyang, Hong Yu


Abstract
Artificial intelligence (AI) and large language models (LLMs) in healthcare require advanced clinical skills (CS), yet current benchmarks fail to evaluate these comprehensively. We introduce MedQA-CS, an AI-SCE framework inspired by medical education’s Objective Structured Clinical Examinations (OSCEs), to address this gap. MedQA-CS evaluates LLMs through two instruction-following tasks—LLM-as-medical-student and LLM-as-CS-examiner—designed to reflect real clinical scenarios. Our contributions include developing MedQA-CS, a comprehensive evaluation framework with publicly available data and expert annotations, and providing the quantitative and qualitative assessment of LLMs as reliable judges in CS evaluation. Our experiments show that MedQA-CS is a more challenging benchmark for evaluating clinical skills than traditional multiple-choice QA benchmarks (e.g., MedQA). Combined with existing benchmarks, MedQA-CS enables a more comprehensive evaluation of LLMs’ clinical capabilities for both open- and closed-source LLMs.
Anthology ID:
2026.eacl-long.292
Volume:
Proceedings of the 19th Conference of the European Chapter of the Association for Computational Linguistics (Volume 1: Long Papers)
Month:
March
Year:
2026
Address:
Rabat, Morocco
Editors:
Vera Demberg, Kentaro Inui, Lluís Marquez
Venue:
EACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
6183–6257
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URL:
https://preview.aclanthology.org/ingest-eacl/2026.eacl-long.292/
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Cite (ACL):
Zonghai Yao, Zihao Zhang, Chaolong Tang, Xingyu Bian, Youxia Zhao, Zhichao Yang, Junda Wang, Huixue Zhou, Won Seok Jang, Feiyun Ouyang, and Hong Yu. 2026. MedQA-CS: Objective Structured Clinical Examination (OSCE)-Style Benchmark for Evaluating LLM Clinical Skills. In Proceedings of the 19th Conference of the European Chapter of the Association for Computational Linguistics (Volume 1: Long Papers), pages 6183–6257, Rabat, Morocco. Association for Computational Linguistics.
Cite (Informal):
MedQA-CS: Objective Structured Clinical Examination (OSCE)-Style Benchmark for Evaluating LLM Clinical Skills (Yao et al., EACL 2026)
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https://preview.aclanthology.org/ingest-eacl/2026.eacl-long.292.pdf