ClinicalTrialsHub: Bridging Registries and Literature for Comprehensive Clinical Trial Access

Jiwoo Park, Ruoqi Liu, Avani Jagdale, Andrew Srisuwananukorn, Jing Zhao, Ping Zhang, Sachin Kumar


Abstract
We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles. Our system effectively increases access to structured clinical trial data by 83.8% compared to relying on ClinicalTrials.gov alone, with potential to make access easier for patients, clinicians, researchers, and policymakers, advancing evidence-based medicine. ClinicalTrialsHub uses large language models such as GPT-5.1 and Gemini-3-Pro to enhance accessibility. The platform automatically parses full-text research articles to extract structured trial information, translates user queries into structured database searches, and provides an attributed question-answering system that generates evidence-grounded answers linked to specific source sentences. We demonstrate its utility through a user study involving clinicians, clinical researchers, and PhD students of pharmaceutical sciences and nursing, and a systematic automatic evaluation of its information extraction and question answering capabilities.
Anthology ID:
2026.eacl-demo.26
Volume:
Proceedings of the 19th Conference of the European Chapter of the Association for Computational Linguistics (Volume 3: System Demonstrations)
Month:
March
Year:
2026
Address:
Rabat, Marocco
Editors:
Danilo Croce, Jochen Leidner, Nafise Sadat Moosavi
Venue:
EACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
359–396
Language:
URL:
https://preview.aclanthology.org/ingest-eacl/2026.eacl-demo.26/
DOI:
Bibkey:
Cite (ACL):
Jiwoo Park, Ruoqi Liu, Avani Jagdale, Andrew Srisuwananukorn, Jing Zhao, Ping Zhang, and Sachin Kumar. 2026. ClinicalTrialsHub: Bridging Registries and Literature for Comprehensive Clinical Trial Access. In Proceedings of the 19th Conference of the European Chapter of the Association for Computational Linguistics (Volume 3: System Demonstrations), pages 359–396, Rabat, Marocco. Association for Computational Linguistics.
Cite (Informal):
ClinicalTrialsHub: Bridging Registries and Literature for Comprehensive Clinical Trial Access (Park et al., EACL 2026)
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PDF:
https://preview.aclanthology.org/ingest-eacl/2026.eacl-demo.26.pdf