Intelligent task-oriented dialogue systems (ToDs) are expected to continuously acquire new knowledge, also known as Continual Learning (CL), which is crucial to fit ever-changing user needs. However, catastrophic forgetting dramatically degrades the model performance in face of a long streamed curriculum. In this paper, we aim to overcome the forgetting problem in ToDs and propose a method (HESIT) with hyper-gradient-based exemplar strategy, which samples influential exemplars for periodic retraining. Instead of unilaterally observing data or models, HESIT adopts a profound exemplar selection strategy that considers the general performance of the trained model when selecting exemplars for each task domain. Specifically, HESIT analyzes the training data influence by tracing their hyper-gradient in the optimization process. Furthermore, HESIT avoids estimating Hessian to make it compatible for ToDs with a large pre-trained model. Experimental results show that HESIT effectively alleviates catastrophic forgetting by exemplar selection, and achieves state-of-the-art performance on the largest CL benchmark of ToDs in terms of all metrics.

The development of Large Language Models (LLMs) has greatly advanced the field of drug discovery, with the belief that natural language can enhance human control over molecule design. However, the scarcity of high-quality labeled data remains a challenge for cross text-molecule learning. Existing datasets are limited due to the difficulty of collecting precise molecule-description pairs. Although recent efforts have utilized pseudo data generated by LLMs for augmentation, the lack of specialized chemistry knowledge of LLMs and the absence of an effective high quality data selector may introduce noise into the annotations, compromising the models’ robustness. To address these challenges, this paper introduces a novel framework that interweaves model fine-tuning and data augmentation to overcome the scarcity of high-quality data. The proposed approach involves an iterative procedure where the model plays dual roles in annotating unlabeled data and sampling a subset of high-quality data until convergence is achieved, enhancing the model’s understanding and adaptability. Additionally, a new dataset called SAPubChem-41 is presented, which comprises meticulously curated high-quality parallel molecule-description pairs designed specifically for fine-tuning purposes. This research provides an important contribution to the field by addressing the need for high-quality datasets and presenting an effective framework for cross text-molecule learning.

Despite recent successes in natural language processing and computer vision, Transformer faces scalability issues when processing graphs, e.g., computing the full node-to-node attention on knowledge graphs (KGs) with million of entities is still infeasible. The existing methods mitigate this problem by considering only the local neighbors, sacrificing the Transformer’s ability to attend to elements at any distance. This paper proposes a new Transformer architecture called Dual-Encoding Transformer (DET). DET comprises a structural encoder to aggregate information from nearby neighbors, and a semantic encoder to seek for semantically relevant nodes. We adopt a semantic neighbor search approach inspired by multiple sequence alignment (MSA) algorithms used in biological sciences. By stacking the two encoders alternately, similar to the MSA Transformer for protein representation, our method achieves superior performance compared to state-of-the-art attention-based methods on complex relational graphs like KGs and citation networks. Additionally, DET remains competitive for smaller graphs such as molecules.

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM that possesses bidirectional generation capabilities in both human and protein languages: (i) taking a protein sequence as input to predict its textual function description and (ii) using natural language to prompt protein sequence generation. To achieve this, we first pre-train an LLM on both protein and natural language corpora, enabling it to comprehend individual languages. Then supervised instruction tuning is employed to facilitate the alignment of these two distinct languages. Herein, we introduce a knowledge graph-based instruction generation framework to construct a high-quality instruction dataset, addressing the annotation imbalance and the absence of instructional signals in the existing protein-text corpus. In particular, the instructions inherit the structural relations between proteins and function annotations in knowledge graphs, which empowers our model to engage in the causal modeling of protein functions, akin to the chain-of-thought processes in natural languages. Extensive experiments on bidirectional protein-text generation tasks show that InstructProtein outperforms state-of-the-art LLMs by a large margin.

Existing dialogue models may encounter scenarios which are not well-represented in the training data, and as a result generate responses that are unnatural, inappropriate, or unhelpful. We propose the “Ask an Expert” framework in which the model is trained with access to an “expert” which it can consult at each turn. Advice is solicited via a structured dialogue with the expert, and the model is optimized to selectively utilize (or ignore) it given the context and dialogue history. In this work the expert takes the form of an LLM.We evaluate this framework in a mental health support domain, where the structure of the expert conversation is outlined by pre-specified prompts which reflect a reasoning strategy taught to practitioners in the field. Blenderbot models utilizing “Ask an Expert” show quality improvements across all expert sizes, including those with fewer parameters than the dialogue model itself. Our best model provides a ~10% improvement over baselines, approaching human-level scores on “engingingness” and “helpfulness” metrics.

Knowing how to end and resume conversations over time is a natural part of communication, allowing for discussions to span weeks, months, or years. The duration of gaps between conversations dictates which topics are relevant and which questions to ask, and dialogue systems which do not explicitly model time may generate responses that are unnatural. In this work we explore the idea of making dialogue models aware of time, and present GapChat, a multi-session dialogue dataset in which the time between each session varies. While the dataset is constructed in real-time, progress on events in speakers’ lives is simulated in order to create realistic dialogues occurring across a long timespan. We expose time information to the model and compare different representations of time and event progress. In human evaluation we show that time-aware models perform better in metrics that judge the relevance of the chosen topics and the information gained from the conversation.

Key information extraction (KIE) from scanned documents has gained increasing attention because of its applications in various domains. Although promising results have been achieved by some recent KIE approaches, they are usually built based on discriminative models, which lack the ability to handle optical character recognition (OCR) errors and require laborious token-level labeling. In this paper, we propose a novel generative end-to-end model, named GenKIE, to address the KIE task. GenKIE is a sequence-to-sequence multimodal generative model that utilizes multimodal encoders to embed visual, layout and textual features and a decoder to generate the desired output. Well-designed prompts are leveraged to incorporate the label semantics as the weakly supervised signals and entice the generation of the key information. One notable advantage of the generative model is that it enables automatic correction of OCR errors. Besides, token-level granular annotation is not required. Extensive experiments on multiple public real-world datasets show that GenKIE effectively generalizes over different types of documents and achieves state-of-the-art results. Our experiments also validate the model’s robustness against OCR errors, making GenKIE highly applicable in real-world scenarios.

The ability to understand a user’s underlying needs is critical for conversational systems, especially with limited input from users in a conversation. Thus, in such a domain, Asking Clarification Questions (ACQs) to reveal users’ true intent from their queries or utterances arise as an essential task. However, it is noticeable that a key limitation of the existing ACQs studies is their incomparability, from inconsistent use of data, distinct experimental setups and evaluation strategies. Therefore, in this paper, to assist the development of ACQs techniques, we comprehensively analyse the current ACQs research status, which offers a detailed comparison of publicly available datasets, and discusses the applied evaluation metrics, joined with benchmarks for multiple ACQs-related tasks. In particular, given a thorough analysis of the ACQs task, we discuss a number of corresponding research directions for the investigation of ACQs as well as the development of conversational systems.

Embedding-based methods have attracted increasing attention in recent entity alignment (EA) studies. Although great promise they can offer, there are still several limitations. The most notable is that they identify the aligned entities based on cosine similarity, ignoring the semantics underlying the embeddings themselves. Furthermore, these methods are shortsighted, heuristically selecting the closest entity as the target and allowing multiple entities to match the same candidate. To address these limitations, we model entity alignment as a sequential decision-making task, in which an agent sequentially decides whether two entities are matched or mismatched based on their representation vectors. The proposed reinforcement learning (RL)-based entity alignment framework can be flexibly adapted to most embedding-based EA methods. The experimental results demonstrate that it consistently advances the performance of several state-of-the-art methods, with a maximum improvement of 31.1% on Hits@1.

We introduce the task of implicit offensive text detection in dialogues, where a statement may have either an offensive or non-offensive interpretation, depending on the listener and context. We argue that reasoning is crucial for understanding this broader class of offensive utterances, and release SLIGHT, a dataset to support research on this task. Experiments using the data show that state-of-the-art methods of offense detection perform poorly when asked to detect implicitly offensive statements, achieving only ∼ 11% accuracy. In contrast to existing offensive text detection datasets, SLIGHT features human-annotated chains of reasoning which describe the mental process by which an offensive interpretation can be reached from each ambiguous statement. We explore the potential for a multi-hop reasoning approach by utilizing existing entailment models to score the probability of these chains, and show that even naive reasoning models can yield improved performance in most situations. Analysis of the chains provides insight into the human interpretation process and emphasizes the importance of incorporating additional commonsense knowledge.

Dialogue State Tracking (DST) aims to keep track of users’ intentions during the course of a conversation. In DST, modelling the relations among domains and slots is still an under-studied problem. Existing approaches that have considered such relations generally fall short in: (1) fusing prior slot-domain membership relations and dialogue-aware dynamic slot relations explicitly, and (2) generalizing to unseen domains. To address these issues, we propose a novel Dynamic Schema Graph Fusion Network (DSGFNet), which generates a dynamic schema graph to explicitly fuse the prior slot-domain membership relations and dialogue-aware dynamic slot relations. It also uses the schemata to facilitate knowledge transfer to new domains. DSGFNet consists of a dialogue utterance encoder, a schema graph encoder, a dialogue-aware schema graph evolving network, and a schema graph enhanced dialogue state decoder. Empirical results on benchmark datasets (i.e., SGD, MultiWOZ2.1, and MultiWOZ2.2), show that DSGFNet outperforms existing methods.