SCaLER@ALTA 2025: Hybrid and Bi-Encoder Approaches for Adverse Drug Event Mention Normalization

Shelke Akshay Babasaheb, Anand Kumar Madasamy


Abstract
This paper describes the system developed by Team Scaler for the ALTA 2025 Shared Task on Adverse Drug Event (ADE) Mention Normalization. The task aims to normalize freetext mentions of adverse events to standardized MedDRA concepts. We present and compare two architectures: (1) a Hybrid Candidate Generation + Neural Reranker approach using a pretrained PubMedBERT model, and (2) a BiEncoder model based on SapBERT, fine-tuned to align ADE mentions with MedDRA concepts. The hybrid approach retrieves candidate terms through semantic similarity search and refines the ranking using a neural reranker, while the bi-encoder jointly embeds mentions and concepts into a shared semantic space. On the development set, the hybrid reranker achieves Accuracy@1 = 0.3840, outperforming the bi-encoder (Accuracy@1 = 0.3298). The bi-encoder system was used for official submission and ranked third overall in the competition. Our analysis highlights the complementary strengths of both retrieval-based and embedding-based normalization strategies.
Anthology ID:
2025.alta-main.17
Volume:
Proceedings of The 23rd Annual Workshop of the Australasian Language Technology Association
Month:
November
Year:
2025
Address:
Sydney, Australia
Editors:
Jonathan K. Kummerfeld, Aditya Joshi, Mark Dras
Venue:
ALTA
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
224–229
Language:
URL:
https://preview.aclanthology.org/ingest-alta/2025.alta-main.17/
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Bibkey:
Cite (ACL):
Shelke Akshay Babasaheb and Anand Kumar Madasamy. 2025. SCaLER@ALTA 2025: Hybrid and Bi-Encoder Approaches for Adverse Drug Event Mention Normalization. In Proceedings of The 23rd Annual Workshop of the Australasian Language Technology Association, pages 224–229, Sydney, Australia. Association for Computational Linguistics.
Cite (Informal):
SCaLER@ALTA 2025: Hybrid and Bi-Encoder Approaches for Adverse Drug Event Mention Normalization (Babasaheb & Madasamy, ALTA 2025)
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https://preview.aclanthology.org/ingest-alta/2025.alta-main.17.pdf