Existing LLM hallucination mitigation methods, including prompt engineering and model optimization, either hardly alter models’ internal knowledge or have poor cross-domain generalization. Contrastive decoding mitigates hallucinations by using layer-wise differences in LLMs. However, prior studies only explore transformer-based models (e.g., GPT), ignoring other effective frameworks like mixture-of-experts (MoE) models. Since MoE alters the traditional transformer architecture, we conduct empirical studies to investigate whether similar layer-wise differences exist in MoEs. Our results show that they do not exist in MoE with shared experts; nevertheless, across different MoEs, higher layers exhibit distinct expert activation patterns between factual and non-factual outputs. Building on these, we propose EAACD, an expert-aware adaptive contrast decoding that uses expert differences in MoE’s higher layers to mitigate hallucinations on QA tasks. EAACD splits high-layer experts into a higher-reliability group and several lower-reliability groups based on their confidence and consistency. It contrasts the higher-reliability group’s prediction with each lower-reliability group’s prediction to calibrate the model’s original predictions. To strengthen this contrast, EAACD amplifies hallucinations from lower-reliability experts via attention and masking to provide stronger negative references. EAACD outperforms all baselines on four datasets