Recent advancements in Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in interpreting single medical images. However, real-world clinical diagnosis is intrinsically a multi-view process, requiring the synthesis of information across volumetric slices, temporal sequences, and comparative modalities. Existing benchmarks fail to capture this complexity, limiting the assessment of models in realistic clinical workflows. To bridge this gap, we introduce MedMultiBench, the first large-scale benchmark specifically designed for medical multi-image understanding. Comprising 11,392 expert-curated samples, MedMultiBench evaluates MLLMs across four distinct dimensions: Joint Reasoning, Comparative Analysis, Comprehensive Perception, and In-Context Learning. We benchmark 13 state-of-the-art MLLMs, revealing that while current models excel in single-view tasks, they struggle significantly with multi-image contexts. Our experiments identify a performance degradation in open-source models when processing increased visual loads, whereas closed-source models demonstrate better scalability. MedMultiBench provides a robust framework to facilitate the development of MLLMs capable of holistic clinical reasoning.

Medical visual question answering (MVQA) requires in-depth understanding of medical images and questions to provide reliable answers. We summarize multi-level progressive capabilities that models need to focus on in MVQA: recognition, details, diagnosis, knowledge, and reasoning. Existing MVQA models tend to ignore the above capabilities due to unspecific data and plain architecture. To address these issues, this paper proposes Multi-level Visual Language Model (MLeVLM) for MVQA. On the data side, we construct a high-quality multi-level instruction dataset MLe-VQA via GPT-4, which covers multi-level questions and answers as well as reasoning processes from visual clues to semantic cognition. On the architecture side, we propose a multi-level feature alignment module, including attention-based token selector and context merger, which can efficiently align features at different levels from visual to semantic. To better evaluate the model’s capabilities, we manually construct a multi-level MVQA evaluation benchmark named MLe-Bench. Extensive experiments demonstrate the effectiveness of our constructed multi-level instruction dataset and the multi-level feature alignment module. It also proves that MLeVLM outperforms existing medical multimodal large language models.

Large Language Models (LLMs) have made significant progress recently. However, their practical use in healthcare is hindered by their tendency to generate hallucinations. One specific type, called snowballing hallucination, occurs when LLMs encounter misleading information, and poses a security threat to LLMs. To understand how well LLMs can resist these hallucination, we create the Chinese Medical Hallucination Evaluation benchmark (CMHE). This benchmark can be used to evaluate LLMs’ ability to detect medical hallucinations, make accurate diagnoses in noisy conditions, and provide plausible explanations. The creation of this benchmark involves a combination of manual and model-based approaches. In addition, we use ICD-10 as well as MeSH, two specialized glossaries, to aid in the evaluation. Our experiments show that the LLM struggles to identify fake medical terms and makes poor diagnoses in distracting environments. However, improving the model’s understanding of medical concepts can help it resist interference to some extent. Our dataset is available at https://drive.google.com/drive/folders/1DrdovKwZIh6AX_JjL8BVpUmI9djiIwn_?usp=drive_link.