Autonomous LLM agents increasingly operate in long-horizon, interactive settings where success depends on reusing experience accumulated over extended histories. However, existing agent memory systems are fundamentally constrained by text-context budgets: storing or revisiting raw trajectories is prohibitively token-expensive, while summarization and text-only retrieval trade token savings for information loss and fragmented evidence. To address this limitation, we propose Optical Context Retrieval Memory (**OCR-Memory**), a memory framework that leverages the visual modality as a high-density representation of agent experience, enabling retention of arbitrarily long histories with minimal prompt overhead at retrieval time. Specifically, OCR-Memory renders historical trajectories into images annotated with unique visual identifiers. OCR-Memory retrieves stored experience via a locate-and-transcribe paradigm that selects relevant regions through visual anchors and retrieves the corresponding verbatim text, avoiding free-form generation and reducing hallucination. Experiments on long-horizon agent benchmarks show consistent gains under strict context limits, demonstrating that optical encoding increases effective memory capacity while preserving faithful evidence recovery.

Large Language Models (LLMs) are increasingly adopted as conversational assistants in genomics, where they are mainly used to reason over biological knowledge, annotations, and analysis outputs through natural language interfaces. However, existing benchmarks either focus on specialized DNA models trained for sequence prediction or evaluate biological knowledge using text-only questions, leaving the behavior of general-purpose LLMs when directly exposed to raw genome sequences underexplored. We introduce GenomeQA, a benchmark designed to provide a controlled evaluation setting for general-purpose LLMs on sequence-based genome inference tasks. GenomeQA comprises 5,200 samples drawn from multiple biological databases, with sequence lengths ranging from 6 to 1,000 base pairs (bp), spanning six task families: Enhancer and Promoter Identification, Splice Site Identification, Taxonomic Classification, Histone Mark Prediction, Transcription Factor Binding Site Prediction, and TF Motif Prediction. Across six frontier LLMs, we find that models often outperform random baselines, particularly on tasks driven by local sequence cues such as GC content and short motifs, while performance degrades on tasks that require more indirect or multi-step inference over sequence patterns. GenomeQA establishes a diagnostic benchmark for studying and improving the use of general-purpose LLMs on raw genomic sequences.