Automated interaction with graphical user interfaces (GUIs) is central to General Artificial Intelligence yet remains challenging within Super App ecosystems, characterized by non-standard rendering and absent accessibility metadata. While GUI agents often rely on explicit accessibility trees or static imitation, they are less explored for dynamic environments marked by sparse feedback and implicit visual cues. We present GUI0, a framework synergizing autonomous data synthesis with dual-agent co-evolution. GUI0 establishes a domain-aware foundation model via synthesized corpora and employs curriculum-driven reinforcement learning, where a curriculum agent generates boundary tasks to optimize an actor agent.Empirical results demonstrate three key advantages: (1) State-of-the-art performance on the SuperAPP benchmark, outperforming Gemini-2.5-Pro and Claude-4-Sonnet; (2) universal efficacy across diverse base models, consistently yielding substantial improvements on both Qwen2.5-VL and GUI-Owl variants; and (3) robust zero-shot generalization to standard GUIs (e.g., +62.7% on ScreenSpot Pro).