Lightweight Vision-Language Models (VLMs) are indispensable for resource-constrained applications. The prevailing approach to aligning vision and language models involves freezing both the vision encoder and the language model while training small connector modules. However, this strategy heavily depends on the intrinsic capabilities of the language model, which can be suboptimal for lightweight models with limited representational capacity. In this work, we investigate this alignment bottleneck through the lens of mutual information, positing that the constrained capacity of the language model inherently limits the Effective Mutual Information (EMI) between multimodal inputs and outputs, thereby compromising alignment quality. To address this challenge, we propose TinyAlign, a novel framework inspired by Retrieval-Augmented Generation, which strategically retrieves relevant context from a memory bank constructed from training data to enrich multimodal inputs and enhance their alignment. Extensive empirical evaluations reveal that TinyAlign significantly reduces training loss, accelerates convergence, and enhances task performance with negligible computational overhead. Remarkably, it allows models to achieve baseline-level performance with only 40% of the fine-tuning data, highlighting exceptional data efficiency. Our work thus offers a practical pathway for developing more capable lightweight VLMs while introducing a fresh theoretical lens to better understand and address alignment bottlenecks in constrained multimodal systems.

Vision–Language Models (VLMs) excel at visual reasoning but still struggle with external knowledge integration. Retrieval-Augmented Generation(RAG) is a promising solution, but current methods remain inefficient and often fail to maintain high answer quality. To address these challenges, we propose VideoSpeculateRAG, an efficient VLM-based RAG framework built on two key ideas. First, we introduce a speculative decoding pipeline: a lightweight draft model quickly generates multiple answer candidates, which are then verified and refined by a more accurate heavyweight model, substantially reducing inference latency without sacrificing correctness. Second, we identify a major source of error, incorrect entity recognition in retrieved knowledge, and mitigate it with a simple yet effective similarity-based filtering strategy that improves entity alignment and boosts overall answer accuracy. Experiments demonstrate that VideoSpeculateRAG achieves comparable or higher accuracy than standard RAG approaches, while speeding up the inference by approximately 2x. Our framework highlights the potential of combining speculative decoding with retrieval-augmented reasoning to enhance efficiency and reliability in complex, knowledge-intensive multimodal tasks.

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability.Recently, Large Language Models (LLMs) have been widely adopted in healthcare due to their extensive knowledge reserves, retrieval, and communication capabilities. While LLMs show promise and excel at medical benchmarks, their diagnostic reasoning and inquiry skills are constrained.To mitigate this issue, we propose (1) Clinical Diagnostic Reasoning Data (CDRD) structure to capture abstract clinical reasoning logic, and a pipeline for its construction, and (2) the Dr. Assistant, a clinical diagnostic model equipped with clinical reasoning and inquiry skills. Its training involves a two-stage process: SFT, followed by RL with a tailored reward function.We also introduce a benchmark to evaluate both diagnostic reasoning and inquiry.Our experiments demonstrate that the Dr. Assistant outperforms open-source models and achieves competitive performance to closed-source models, providing an effective solution for clinical diagnostic inquiry guidance. Project information can be found at: https://github.com/YGswu/Dr.-Assistant.