If Only My CGM Could Speak: A Privacy-Preserving Agent for Question Answering over Continuous Glucose Data

Yanjun Cui, Ali Emami, Temiloluwa Prioleau, Nikhil Singh


Abstract
Continuous glucose monitors (CGMs) used in diabetes care collect rich personal health data that could improve day-to-day self-management. However, current patient platforms only offer static summaries which do not support inquisitive user queries. Large language models (LLMs) could enable free-form inquiries about continuous glucose data, but deploying them over sensitive health records raises privacy and accuracy concerns. In this paper, we present **CGM-Agent**, a privacy-preserving framework for question answering over personal glucose data. In our design, the LLM serves purely as a reasoning engine that selects analytical functions. All computation occurs locally, and personal health data never leaves the user’s device. For evaluation, we construct a benchmark of 4,180 questions combining parameterized question templates with real user queries and ground truth derived from deterministic program execution. Evaluating 6 leading LLMs, we find that top models achieve 94% value accuracy on synthetic queries and 88% on ambiguous real-world queries. Errors stem primarily from intent and temporal ambiguity rather than computational failures. Additionally, lightweight models achieve competitive performance in our agent design, suggesting opportunities for low-cost deployment. We release our code and benchmark to support future work on trustworthy health agents.
Anthology ID:
2026.findings-acl.891
Volume:
Findings of the Association for Computational Linguistics: ACL 2026
Month:
July
Year:
2026
Address:
San Diego, California, United States
Editors:
Maria Liakata, Viviane P. Moreira, Jiajun Zhang, David Jurgens
Venue:
Findings
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Publisher:
Association for Computational Linguistics
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Pages:
17941–17958
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URL:
https://preview.aclanthology.org/ingest-acl/2026.findings-acl.891/
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Cite (ACL):
Yanjun Cui, Ali Emami, Temiloluwa Prioleau, and Nikhil Singh. 2026. If Only My CGM Could Speak: A Privacy-Preserving Agent for Question Answering over Continuous Glucose Data. In Findings of the Association for Computational Linguistics: ACL 2026, pages 17941–17958, San Diego, California, United States. Association for Computational Linguistics.
Cite (Informal):
If Only My CGM Could Speak: A Privacy-Preserving Agent for Question Answering over Continuous Glucose Data (Cui et al., Findings 2026)
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https://preview.aclanthology.org/ingest-acl/2026.findings-acl.891.pdf
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