Probabilistic Depression Detection from Textual Time Series

Fabian Schmidt, Seyedehmoniba Ravan, Vladimir Vlassov


Abstract
Accurate and interpretable predictions of depression severity are essential for clinical decision support, yet existing models often lack uncertainty estimates and temporal interpretability. We propose PTTSD, a Probabilistic framework for Depression Detection from clinical interview utterance sequences that predicts PHQ-8 scores while modeling calibrated uncertainty. PTTSD includes sequence-to-sequence and sequence-to-one variants, both combining LSTMs, self-attention, and residual connections with Gaussian or Student’s-t output heads trained via negative log-likelihood. The sequence-to-sequence variant enables temporal analysis of how predictive confidence evolves over an interview, despite the target being a single session-level score. Evaluated on E-DAIC and DAIC-WOZ, PTTSD achieves competitive performance among text-only systems (e.g., MAE = 3.85 on E-DAIC, 3.55 on DAIC) and produces well-calibrated prediction intervals. Ablations confirm the value of attention and probabilistic modeling, while a three-part calibration analysis and qualitative case studies highlight the clinical relevance of uncertainty-aware prediction.
Anthology ID:
2026.findings-acl.1630
Volume:
Findings of the Association for Computational Linguistics: ACL 2026
Month:
July
Year:
2026
Address:
San Diego, California, United States
Editors:
Maria Liakata, Viviane P. Moreira, Jiajun Zhang, David Jurgens
Venue:
Findings
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Publisher:
Association for Computational Linguistics
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Pages:
32574–32589
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URL:
https://preview.aclanthology.org/ingest-acl/2026.findings-acl.1630/
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Cite (ACL):
Fabian Schmidt, Seyedehmoniba Ravan, and Vladimir Vlassov. 2026. Probabilistic Depression Detection from Textual Time Series. In Findings of the Association for Computational Linguistics: ACL 2026, pages 32574–32589, San Diego, California, United States. Association for Computational Linguistics.
Cite (Informal):
Probabilistic Depression Detection from Textual Time Series (Schmidt et al., Findings 2026)
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