Experiments or Outcomes? Probing Scientific Feasibility in Large Language Models

Seyedali Mohammadi, Manas Gaur, Francis Ferraro


Abstract
Scientific feasibility assessment asks whether a claim is consistent with established knowledge and whether experimental evidence could support or refute it. We frame feasibility assessment as a diagnostic reasoning task in which, given a hypothesis, a model predicts feasible or infeasible and justifies its decision. We evaluate large language models (LLMs) under controlled knowledge conditions (hypothesis-only, with experiments, with outcomes, or both) and probe robustness by progressively removing portions of the experimental and/or outcome context. Across multiple LLMs and two datasets, providing outcome evidence is generally more reliable than providing experiment descriptions. Outcomes tend to improve accuracy beyond what internal knowledge alone provides, whereas experimental text can be brittle and may degrade performance when the context is incomplete. These findings clarify when experimental evidence benefits LLM-based feasibility assessment and when it introduces fragility.
Anthology ID:
2026.acl-short.50
Volume:
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 2: Short Papers)
Month:
July
Year:
2026
Address:
San Diego, California, United States
Editors:
Maria Liakata, Viviane P. Moreira, Jiajun Zhang, David Jurgens
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ACL
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Publisher:
Association for Computational Linguistics
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Pages:
605–614
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URL:
https://preview.aclanthology.org/ingest-acl/2026.acl-short.50/
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Cite (ACL):
Seyedali Mohammadi, Manas Gaur, and Francis Ferraro. 2026. Experiments or Outcomes? Probing Scientific Feasibility in Large Language Models. In Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 2: Short Papers), pages 605–614, San Diego, California, United States. Association for Computational Linguistics.
Cite (Informal):
Experiments or Outcomes? Probing Scientific Feasibility in Large Language Models (Mohammadi et al., ACL 2026)
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