Empathy in Diversity: Personalized Depression and Anxiety Therapy via Dialogue State Tracking and Patient-Aware Planning

Xinwei Yang, Junyi Fan, Yuqing Liu, Jiaxuan Wang, Jiashuai Zhang, Hongru Liang, Wenqiang Lei, Yao Song


Abstract
Large language model (LLM) dialogue agents are increasingly used in psychological therapy, yet robustness across diverse patients remains underexplored. We address this gap with three contributions: (1) MindEval, a realistic role-play protocol for evaluating therapeutic dialogue agents; (2) MindData, a de-identified, expert-annotated corpus of therapist–patient dialogues (2,573 sessions; 63,348 turns); and (3) MindApt, a framework that integrates a therapeutic dialogue state tracking paradigm with a patient-aware strategic planning module. On MindEval, MindApt outperforms strong baselines on therapeutic outcomes and dialogue quality while improving conversational efficiency. To evaluate utility beyond role-play, we conducted a clinical study with real patients, demonstrating that MindApt-guided care achieves outcomes comparable to therapist-determined care, while the hybrid setting combining therapist judgment with MindApt’s recommendations yields the strongest overall outcomes.
Anthology ID:
2026.acl-long.424
Volume:
Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
Month:
July
Year:
2026
Address:
San Diego, California, United States
Editors:
Maria Liakata, Viviane P. Moreira, Jiajun Zhang, David Jurgens
Venue:
ACL
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Publisher:
Association for Computational Linguistics
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Pages:
9370–9416
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URL:
https://preview.aclanthology.org/ingest-acl/2026.acl-long.424/
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Cite (ACL):
Xinwei Yang, Junyi Fan, Yuqing Liu, Jiaxuan Wang, Jiashuai Zhang, Hongru Liang, Wenqiang Lei, and Yao Song. 2026. Empathy in Diversity: Personalized Depression and Anxiety Therapy via Dialogue State Tracking and Patient-Aware Planning. In Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers), pages 9370–9416, San Diego, California, United States. Association for Computational Linguistics.
Cite (Informal):
Empathy in Diversity: Personalized Depression and Anxiety Therapy via Dialogue State Tracking and Patient-Aware Planning (Yang et al., ACL 2026)
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